Evidence map›Paper›PMID 35174540›Full record

ArticleJournal of gastroenterology and hepatology2022

Outcomes for upper gastrointestinal bleeding during the first wave of the COVID-19 pandemic in the Toronto area.

Rishad Khan, Sudipta Saha, Nikko Gimpaya, Rishi Bansal, Michael A Scaffidi, Fahad Razak, Amol A Verma, Samir C Grover

Open access · greenAbstract read
In one paragraph

Article in Journal of gastroenterology and hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Gastrointestinal Bleeding in COVID-19-Infected Patients.Gastroenterology clinics of North America · 2023
    Review
  7. Article
  8. Observational
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rishad KhanDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-5090-7685
Sudipta SahaLi Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.
Nikko GimpayaDivision of Gastroenterology, St. Michael's Hospital, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-1015-4372
Rishi BansalDivision of Gastroenterology, St. Michael's Hospital, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-4381-7945
Michael A ScaffidiDivision of Gastroenterology, St. Michael's Hospital, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-2068-6655
Fahad RazakDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada.
Amol A VermaDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-6857-931X
Samir C GroverDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-3392-1220
St. Michael's Hospital · CAUniversity of Toronto · CA

Funding

St. Michael's Hospital Foundation SMH-20-034
6 · The paper itself

Abstract

BACKGROUND AND

aimChanges to endoscopy service availability during the COVID-19 pandemic may have affected management of upper gastrointestinal bleeding (UGIB). The aim of this study was to describe the impact of the pandemic on UGIB outcomes in the Toronto area in Canada.

methodsWe described all adults admitted to general medicine wards or intensive care units at six hospitals in Toronto and Mississauga, Canada, with UGIB during the first wave of the COVID-19 pandemic (March 1 to June 30, 2020) and compared them with a historical cohort (March 1 to June 30, 2018 and 2019). We compared clinical outcomes (in-hospital mortality, length of stay, 30-day readmission, intensive care utilization, receipt of endoscopy, persistent bleeding, receipt of second endoscopy, and need for angiographic or surgical intervention) using multivariable regression models, controlling for demographics, comorbidities, and severity of clinical presentation.

resultsThere were 82.5 and 215.5 admissions per month for UGIB during the COVID-19 and control periods, respectively. There were no baseline differences between groups for demographic characteristics, comorbidities, or severity of bleeding. Patients in the COVID-19 group did not have significantly different unadjusted (3.9% vs 4.2%, P = 0.983) or adjusted mortality (adjusted odds ratio [OR] = 0.64, 95% confidence interval [CI] = 0.25-1.48, P = 0.322). Patients in COVID-19 group were less likely to receive endoscopy for UGIB in the unadjusted (61.8% vs 71.0%, P = 0.003) and adjusted (adjusted OR = 0.64, 95% CI = 0.49-0.84, P < 0.01) models. There were no differences between groups for other secondary outcomes.

conclusionsWhile patients admitted for UGIB during the first wave of the pandemic were less likely to receive endoscopy, this had no impact on mortality or any secondary outcomes.

Indexed as

COVID-19AdultEndoscopy, GastrointestinalGastrointestinal HemorrhageHospital MortalityHumansPandemicsRetrospective StudiesCOVID-19endoscopygastrointestinal hemorrhage

Identifiers

PMID35174540
PMCPMC9115050
OpenAlexW4213244484

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.