Evidence map›Paper›PMID 35177672›Full record

ArticleScientific reports2022

Whole-transcriptome analysis and construction of an anther development-related ceRNA network in Chinese cabbage (Brassica campestris L. ssp. pekinensis).

Fengyan Shi, Zhijin Pang, Chuanhong Liu, Li Zhou, Chong Tan, Jie Ren, Xueling Ye, Hui Feng, Zhiyong Liu

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07727668 (Feasibility Study of Iberdomide), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07727668 early_phase1not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Feasibility Study of Iberdomide (CC-220) Priming to Improve T Cell Fitness Prior to Leukapheresis for Chimeric Antigen Receptor T Cell (CAR-T) Therapy for Relapsed/Refractory Multiple Myeloma (RRMM)

TypeinterventionalSponsorShambavi RichardRan2026 to 2031Enrolled22ConditionsMultiple Myeloma, Relapsed/Refractory Multiple MyelomaArmsIberdomide, CAR-T Leukapheresis, CAR-T Infusion
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Identification of a new male sterile gene BrATAF1 of Chinese cabbage.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Fengyan Shi *Key Laboratory of Protected Horticulture (Shenyang Agricultural University), Ministry of Education, 120 Dongling Road, Shenhe District, Shenyang, 110866, China.
Zhijin Pang *Key Laboratory of Protected Horticulture (Shenyang Agricultural University), Ministry of Education, 120 Dongling Road, Shenhe District, Shenyang, 110866, China.
Chuanhong LiuKey Laboratory of Protected Horticulture (Shenyang Agricultural University), Ministry of Education, 120 Dongling Road, Shenhe District, Shenyang, 110866, China.
Li ZhouIntegrated Technical Service Center, Bayuquan Customs, Yingkou, 115007, China.
Chong TanKey Laboratory of Protected Horticulture (Shenyang Agricultural University), Ministry of Education, 120 Dongling Road, Shenhe District, Shenyang, 110866, China.
Jie RenKey Laboratory of Protected Horticulture (Shenyang Agricultural University), Ministry of Education, 120 Dongling Road, Shenhe District, Shenyang, 110866, China.
Xueling YeKey Laboratory of Protected Horticulture (Shenyang Agricultural University), Ministry of Education, 120 Dongling Road, Shenhe District, Shenyang, 110866, China.
Hui FengKey Laboratory of Protected Horticulture (Shenyang Agricultural University), Ministry of Education, 120 Dongling Road, Shenhe District, Shenyang, 110866, China.
Zhiyong LiuKey Laboratory of Protected Horticulture (Shenyang Agricultural University), Ministry of Education, 120 Dongling Road, Shenhe District, Shenyang, 110866, China. liuzhiyong99@syau.edu.cn.
Shenyang Agricultural University · CNShanghai Customs College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anther development is precisely regulated by a complex gene network, which is of great significance to plant breeding. However, the molecular mechanism of anther development in Chinese cabbage is unclear. Here, we identified microRNAs (miRNAs), mRNAs, long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs) related to anther development in Chinese cabbage (Brassica campestris L. ssp. pekinensis) to construct competitive endogenous RNA (ceRNA) regulatory networks and provide valuable knowledge on anther development. Using whole-transcriptome sequencing, 9055, 585, 1344, and 165 differentially expressed mRNAs (DEmRNAs), miRNAs (DEmiRNAs), lncRNAs (DElncRNAs), and circRNAs (DEcircRNAs) were identified, respectively, in the anthers of Chinese cabbage compared with those in samples of the vegetative mass of four true leaves. An anther-related ceRNA regulatory network was constructed using miRNA targeting relationships, and 450 pairs of ceRNA relationships, including 97 DEmiRNA-DEmRNA, 281 DEmiRNA-DElncRNA, and 23 DEmiRNA-DEcircRNA interactions, were obtained. We identified important genes and their interactions with lncRNAs, circRNAs, and miRNAs involved in microsporogenesis, tapetum and callose layer development, pollen wall formation, and anther dehiscence. We analyzed the promoter activity of six predominant anther expression genes, which were expressed specifically in the anthers of Arabidopsis thaliana, indicating that they may play an important role in anther development of Chinese cabbage. This study lays the foundation for further research on the molecular mechanisms of anther growth and development in Chinese cabbage.

Indexed as

BrassicaGene Expression Regulation, PlantRNA, PlantGenome-Wide Association StudyTranscriptomeRNA, Plant

Identifiers

PMID35177672
PMCPMC8854722
OpenAlexW4213214055

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.