Evidence map›Paper›PMID 35180016›Full record

SynthesisPharmaceutical biology2022

Phytochemicals with protective effects against acute pancreatitis: a review of recent literature.

Yao Tang, Mingli Sun, Zhenning Liu

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Pharmaceutical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Antidiabetic activity ofFrontiers in nutrition · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Yao TangDepartment of Emergency Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
Mingli SunSchool of Kinesiology, Shenyang Sport University, Shenyang, China.
Zhenning LiuDepartment of Emergency Medicine, Shengjing Hospital of China Medical University, Shenyang, China.ORCID 0000-0003-3202-0914
China Medical University · CNShenyang Sport University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextAcute pancreatitis (AP) is an acute abdominal inflammatory disease with episodes ranging from mild to fulminant symptoms which could include necrosis, systemic inflammation and multiple organ dysfunction. Increasing experimental evidence demonstrates that specific bioactive ingredients from natural plants have a favourable therapeutic effect on AP.

objectiveThe objective of this review is to summarize the protective effects and potential mechanisms of action of phytochemicals on the attenuation of AP.

methodsExperimental studies

resultsA total of 30 phytochemicals with potential therapeutic effects were reviewed and summarized systematically. According to their molecular pathways in AP, the underlying mechanisms of the phytochemicals were illustrated in detail. DISCUSSION AND

conclusionsThe phytochemicals with anti-inflammatory and antioxidant abilities may be efficient candidate drugs for AP treatment. Importantly, more preclinical investigations are needed to illustrate the efficacy of future phytochemicals.

Indexed as

AnimalsAnti-Inflammatory AgentsAntioxidantsHumansMedicine, TraditionalPancreatitisPhytochemicalsPlant PreparationsPlants, MedicinalAnti-Inflammatory AgentsAntioxidantsPhytochemicalsPlant PreparationschemicalsInflammationmolecular mechanismoxidationpancreatic damagesignalling pathway

Identifiers

PMID35180016
PMCPMC8865097
OpenAlexW4212887648

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.