Evidence map›Paper›PMID 35186183›Full record

ArticleOxidative medicine and cellular longevity2022

Tanreqing Injection Regulates Cell Function of Hypoxia-Induced Human Pulmonary Artery Smooth Muscle Cells (HPASMCs) through TRPC1/CX3CL1 Signaling Pathway.

Yonghong Xiang, Fei Zheng, Qinzhe Zhang, RunJuan Zhang, Haiyan Pan, Zongdong Pang, Shimin Dai, Yurong Zhang, Ye Wu, Lunkai Yao and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Yonghong XiangAffiliated Minzu Hospital of Guangxi Medical University, Department of Pulmonary and Critical Care Medicine, Nanning 530001, China.ORCID https://orcid.org/0000-0003-1742-4064
Fei ZhengAffiliated Minzu Hospital of Guangxi Medical University, Department of Pulmonary and Critical Care Medicine, Nanning 530001, China.ORCID https://orcid.org/0000-0002-6150-5892
Qinzhe ZhangAffiliated Minzu Hospital of Guangxi Medical University, Department of Pulmonary and Critical Care Medicine, Nanning 530001, China.ORCID https://orcid.org/0000-0002-8868-6777
RunJuan ZhangAffiliated Minzu Hospital of Guangxi Medical University, Department of Pulmonary and Critical Care Medicine, Nanning 530001, China.ORCID https://orcid.org/0000-0001-7797-5867
Haiyan PanAffiliated Minzu Hospital of Guangxi Medical University, Department of Pulmonary and Critical Care Medicine, Nanning 530001, China.ORCID https://orcid.org/0000-0001-5116-2884
Zongdong PangAffiliated Minzu Hospital of Guangxi Medical University, Department of Pulmonary and Critical Care Medicine, Nanning 530001, China.ORCID https://orcid.org/0000-0003-2725-2833
Shimin DaiAffiliated Minzu Hospital of Guangxi Medical University, Department of Pulmonary and Critical Care Medicine, Nanning 530001, China.ORCID https://orcid.org/0000-0002-3396-723X
Yurong ZhangAffiliated Minzu Hospital of Guangxi Medical University, Department of Pulmonary and Critical Care Medicine, Nanning 530001, China.ORCID https://orcid.org/0000-0001-5862-8341
Ye WuAffiliated Minzu Hospital of Guangxi Medical University, Department of Pulmonary and Critical Care Medicine, Nanning 530001, China.ORCID https://orcid.org/0000-0002-6901-4078
Lunkai YaoAffiliated Minzu Hospital of Guangxi Medical University, Department of Pulmonary and Critical Care Medicine, Nanning 530001, China.ORCID https://orcid.org/0000-0001-8286-8249
Mengju SuAffiliated Minzu Hospital of Guangxi Medical University, Department of Pulmonary and Critical Care Medicine, Nanning 530001, China.ORCID https://orcid.org/0000-0003-4029-1706
Luying LanAffiliated Minzu Hospital of Guangxi Medical University, Department of Pulmonary and Critical Care Medicine, Nanning 530001, China.ORCID https://orcid.org/0000-0003-1111-6220
Guangxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoxia-induced pulmonary arterial hypertension (HPAH) is due to hypoxia caused by vascular endothelial cell remolding and damage. Previous studies have suggested that CX3CL1 plays an important role in HPAH which is affected by oxidative stress. Ca

Indexed as

Cell HypoxiaCell ProliferationChemokine CX3CL1Drugs, Chinese HerbalHumansHypertension, PulmonaryMyocytes, Smooth MusclePulmonary ArteryTRPC Cation ChannelsChemokine CX3CL1Cx3cl1 protein, mouseDrugs, Chinese Herbaltanreqingtransient receptor potential cation channel, subfamily C, member 1TRPC Cation Channels

Identifiers

PMID35186183
PMCPMC8856792
OpenAlexW4211089945

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.