Evidence map›Paper›PMID 35186244›Full record

ArticleJournal of healthcare engineering2022

mir-204-5p Acts as a Tumor Suppressor by Targeting DNM2 in Osteosarcoma Cells.

Liangliang Qu, Zhongqiu Li, Pinduan Liu

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Journal of healthcare engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Liangliang QuDepartment of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou 121001, Liaoning, China.ORCID 0000-0002-8882-6979
Zhongqiu LiDepartment of Hepatobiliary Diseases, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou 121001, Liaoning, China.ORCID 0000-0002-5128-9567
Pinduan LiuDepartment of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou 121001, Liaoning, China.ORCID 0000-0003-4777-8795
Jinzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma is a malignant bone tumor composed of interstitial cells. We aim to seek the function of mir-204-5p/DNM2 in osteosarcoma cells. From April 2017 to August 2019, 58 cases of cancer tissues and paracancer tissues were obtained from patients with osteosarcoma in our hospital. qPCR was used to detect mir-204-5p in excisional cancer tissues and paracarcinoma tissues of osteosarcoma patients. The overexpression vector of mir-204-5p was established and transfected into osteosarcoma cells, and the propagation, invasiveness, migration, and apoptosis of osteosarcoma cells were observed. StarBase was employed to forecast the binding site of mir-204-5p and DNM2. The targeting connection of mir-204-5p with DNM2 was detected via double luciferase reporter gene. mir-204-5p was lessened in osteosarcoma (

Indexed as

Bone NeoplasmsMicroRNAsOsteosarcomaCell Line, TumorCell MovementCell ProliferationDynamin IIGene Expression Regulation, NeoplasticHumansDNM2 protein, humanDynamin IIMicroRNAsMIRN204 microRNA, human

Identifiers

PMID35186244
PMCPMC8849813
OpenAlexW4211157594

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.