ArticleBMJ open2022
Anxiety and depression in Chinese patients with glaucoma and its correlations with vision-related quality of life and visual function indices: a cross-sectional study.
Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The bidirectional enigma of glaucoma and anxiety: from neuroinflammatory mechanisms to mind-body integrated therapies.Frontiers in psychiatry · 2025Pooled it
- From meta-analysis to Mendelian randomization: Unidirectional perspectives on the association of glaucoma with depression and anxiety.PloS one · 2024Pooled it
- Ophthalmic and psychiatric health: the overlooked connection between ocular diseases and mental disorders.Eye (London, England) · 2026Review
- Illness uncertainty, anxiety, and depression in primary glaucoma and associated influencing factors.World journal of psychiatry · 2025Article
- Associations between serum neuropeptide Y levels and anxiety, depression, and quality of life in Chinese patients with primary glaucoma.BMC ophthalmology · 2025Article
- Presence of Anxiety and Depression in Patients with Open-Angle Glaucoma of Different Degrees of Damage.Journal of clinical medicine · 2025Article
- Vision-Related Quality of Life Among Glaucoma Patients in Saudi Arabia:Sultan Qaboos University medical journal · 2025Article
- Blinded by the Mind: Exploring the Hidden Psychiatric Burden in Glaucoma Patients.Biomedicines · 2025Review
- Quality of life and associated factors among patients with glaucoma attending at Boru Meda General Hospital, Northeast Ethiopia.Scientific reports · 2024Article
- Depression and Eye Disease-A Narrative Review of Common Underlying Pathophysiological Mechanisms and their Potential Applications.Journal of clinical medicine · 2024Review
- Arterial spin labeling reveals disordered cerebral perfusion and cerebral blood flow-based functional connectivity in primary open-angle glaucoma.Brain imaging and behavior · 2024Article
- Prevalence of anxiety and depression among patients with glaucoma.Frontiers in psychology · 2024Article
- Impact of Sociodemographic and Psychological Factors on Adherence to Glaucoma Treatment - A Cross-Sectional Study.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Association of aquaporin-4 antibody-seropositive optic neuritis with vision-related quality of life and depression.Frontiers in neurology · 2023Article
- Vision-Related Quality of Life in Primary Angle-Closure Glaucoma Patients with or without Visual Field Dysfunction.Journal of ophthalmology · 2023Article
- Mental health and self-management in glaucoma patients during the COVID-19 pandemic: a cross-sectional study in China.BMC ophthalmology · 2022Article
- Increased probability of mood disorders after age-related macular degeneration: a population-based cohort study.Scientific reports · 2022Article
- Outcomes after combined excisional goniotomy and manual small incision cataract surgery.International journal of ophthalmology · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate anxiety and depression in patients with glaucoma and its correlations with vision-related quality of life (VR-QoL) and visual function indices.
designA hospital-based, cross-sectional study.
settingShanghai, China
participantsThe Hospital Anxiety and Depression Scale and the 25-item National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) were administered to 446 Chinese patients with glaucoma to assess their psychological disorders, namely anxiety and depression, and VR-QoL, respectively. OUTCOME MEASURES: Sociodemographic and clinical data were collected at the same time. Multivariate linear regression analysis was carried out to investigate the associations between VR-QoL, visual function indices and psychological disorders. Standardised partial regression analysis was used to identify the variable mostly indicative in evaluating psychological burdens.
resultsThe prevalence of anxiety and depression in Chinese patients with glaucoma was 12.11% and 25.78%, respectively. Most of the subscales and the composite score of NEI VFQ-25 were negatively associated with each parameter of anxiety and depression after adjusting for sociodemographic and clinical variables. For visual function indices, only the best-corrected visual acuity of both eyes was correlated with anxiety after adjustment. Standardised partial regression analysis further showed VR-QoL, but not the objective visual function indices, was mostly relevant to psychological disturbances.
conclusionsAnxiety and depression were common in Chinese patients with glaucoma. Self-reported VR-QoL was beneficial in assessing psychological status of patients with glaucoma, while objective visual function indices provide little hint on it.
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