ArticleJournal of the American Heart Association2022
Acclimation to a High-Salt Diet Is Sex Dependent.
Open access · goldAbstract read
In one paragraph
Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 37 citations in OpenAlex.
- Salt sensitivity of blood pressure: mechanisms and sex-specific differences.Nature reviews. Cardiology · 2025Review
- Sodium intake and biological sex influence urinary endothelin-1 in salt-resistant adults: a pilot study.American journal of physiology. Regulatory, integrative and comparative physiology · 2025Article
- Renal G protein-coupled estrogen receptor 1 regulates the epithelial sodium channel promoting natriuresis to a greater extent in females.American journal of physiology. Renal physiology · 2025Article
- Endothelin-1 signaling in the kidney: recent advances and remaining gaps.American journal of physiology. Renal physiology · 2025Review
- Prevention of hypertension-induced renal vascular dysfunction through a p66Shc-targeted mechanism.American journal of physiology. Renal physiology · 2025Article
- Aryl Hydrocarbon Receptor Activation Promotes Effector CD4+ T Cell Homeostasis and Restrains Salt-Sensitive Hypertension.Function (Oxford, England) · 2025Article
- Global, regional, and national burden of ischemic heart disease associated with diet high in sodium from 1990 to 2021, and its projections to 2035: a systematic analysis of the global burden of disease study 2021.Frontiers in nutrition · 2025Article
- Maternal high-salt intake induces sex-specific liver injury in offspring: integrative transcriptomic and therapeutic investigation.Frontiers in nutrition · 2025Article
- Early reduction of skin potassium without sodium accumulation in the pathogenesis of salt sensitivity in primary aldosteronism.Frontiers in pharmacology · 2025Article
- Revisiting sex as a biological variable in hypertension research.The Journal of clinical investigation · 2024Review
- A high salt diet impairs the bladder epithelial barrier and activates the NLRP3 and NF‑κB signaling pathways to induce an overactive bladderExperimental and therapeutic medicine · 2024Article
- Interplay of race and neighborhood deprivation on resting and ambulatory blood pressure in young adults.American journal of physiology. Heart and circulatory physiology · 2024Article
- Comprehensive analysis of the endothelin system in the kidneys of mice, rats, and humans.Bioscience reports · 2024Article
- Sex differences in renal transporters: assessment and functional consequences.Nature reviews. Nephrology · 2024Review
- The burden of chronic kidney disease attributable to high sodium intake: a longitudinal study in 1990-2019 in China.Frontiers in nutrition · 2024Article
- Angiotensin II hypertension along the female rat tubule: predicted impact on coupled transport of NaAmerican journal of physiology. Renal physiology · 2023Article
- Endothelin mediates sex-differences in acclimation to high salt diet in rats.Biology of sex differences · 2023Article
- The association between sodium intake and coronary and carotid atherosclerosis in the general Swedish population.European heart journal open · 2023Article
- Salt Sensitivity of Blood Pressure in Women.Hypertension (Dallas, Tex. : 1979) · 2023Review
- G protein-coupled estrogen receptor 1 regulates renal endothelin-1 signaling system in a sex-specific manner.Frontiers in physiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 3 institutions in 1 country.
Eman Y GoharSection of Cardio-Renal Physiology & Medicine Division of Nephrology Department of Medicine University of Alabama at Birmingham AL.ORCID 0000-0003-0988-6445
Carmen De MiguelSection of Cardio-Renal Physiology & Medicine Division of Nephrology Department of Medicine University of Alabama at Birmingham AL.ORCID 0000-0002-2323-3670
Ijeoma E ObiSection of Cardio-Renal Physiology & Medicine Division of Nephrology Department of Medicine University of Alabama at Birmingham AL.
Elizabeth M DaughertySection of Cardio-Renal Physiology & Medicine Division of Nephrology Department of Medicine University of Alabama at Birmingham AL.
Kelly A HyndmanSection of Cardio-Renal Physiology & Medicine Division of Nephrology Department of Medicine University of Alabama at Birmingham AL.
Bryan K BeckerSection of Cardio-Renal Physiology & Medicine Division of Nephrology Department of Medicine University of Alabama at Birmingham AL.
Chunhua JinSection of Cardio-Renal Physiology & Medicine Division of Nephrology Department of Medicine University of Alabama at Birmingham AL.
Randee SedakaSection of Cardio-Renal Physiology & Medicine Division of Nephrology Department of Medicine University of Alabama at Birmingham AL.
Jermaine G JohnstonSection of Cardio-Renal Physiology & Medicine Division of Nephrology Department of Medicine University of Alabama at Birmingham AL.
Pengyuan LiuDepartment of Physiology Medical College of Wisconsin Milwaukee WI.
Joshua S SpeedDepartment of Physiology University of Mississippi Medical Center Jackson MS.
Tanecia MitchellDepartment of Urology University of Alabama at Birmingham AL.ORCID 0000-0002-4032-913X
Alison J KriegelDepartment of Physiology Medical College of Wisconsin Milwaukee WI.
Jennifer S PollockSection of Cardio-Renal Physiology & Medicine Division of Nephrology Department of Medicine University of Alabama at Birmingham AL.
David M PollockSection of Cardio-Renal Physiology & Medicine Division of Nephrology Department of Medicine University of Alabama at Birmingham AL.ORCID 0000-0002-0233-2362
University of Alabama at Birmingham · USMedical College of Wisconsin · USJackson Memorial Hospital · US
Funding
Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9MVascular and renal responses to stressP01HL069999 · NHLBI · MEDICAL COLLEGE OF GEORGIA (MCG) · PI HARSHFIELD, GREGORY ALAN · 2002 to 2018
$31.1MUniversity of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2013 to 2026
$19.5MUAB-UCSD O'Brien Core Center for Acute Kidney Injury ResearchP30DK079337 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AGARWAL, ANUPAM · 2008 to 2022
$18.3MResearch Supplement to Promote DiversityP01HL136267 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI POLLOCK, DAVID M · 2017 to 2021
$11.9MSex hormones and arthritis in a long lived animal modelP30AG050886 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Jianhua Zhang · 2015 to 2026
$11.3MTraining Program in Cell, Molecular, and Developmental BiologyT32GM008111 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI YODER, BRADLEY K. · 1985 to 2022
$5.4MTraining Program in Cardiovascular PathophysiologyT32HL007918 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BALLINGER, SCOTT W. · 1999 to 2018
$3.6MEndothelin-1 in Obesity and Insulin ResistanceR01DK124327 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI SPEED, JOSHUA S · 2021 to 2025
$2.2MUAB KUH KURER25DK115353 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Jennifer S Pollock · 2018 to 2026
$1.0MMonocyte Mitochondrial Dysfunction and Kidney Stone DiseaseK01DK106284 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MITCHELL, TANECIA R · 2016 to 2021
$912kRole of endothelin in hypertension-mediated inflammation and end-organ damageK01HL145324 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DE MIGUEL, CARMEN · 2019 to 2023
$763kNHLBI NIH HHS K01 HL145324NHLBI NIH HHS P01 HL069999NHLBI NIH HHS P01 HL136267NHLBI NIH HHS T32 HL007918NIA NIH HHS P30 AG050886NIDDK NIH HHS F31 DK111067NIDDK NIH HHS K01 DK105038NIDDK NIH HHS K01 DK106284NIDDK NIH HHS K99 DK119413NIDDK NIH HHS P30 DK056336NIDDK NIH HHS P30 DK079337NIDDK NIH HHS P30 DK079626NIDDK NIH HHS R00 DK119413NIDDK NIH HHS R01 DK124327NIDDK NIH HHS R03 DK120503NIDDK NIH HHS R25 DK115353NIGMS NIH HHS T32 GM008111
Abstract
Background Premenopausal women are less likely to develop hypertension and salt-related complications than are men, yet the impact of sex on mechanisms regulating Na
Indexed as
Sodium ChlorideSodium Chloride, DietaryAcclimatizationAnimalsBlood PressureDietEndothelin-1FemaleHumansMaleRatsRats, Sprague-DawleySodiumEndothelin-1SodiumSodium ChlorideSodium Chloride, Dietaryendothelin‐1natriuresisnitric oxidesex differencessodium
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.