Evidence map›Paper›PMID 35194063›Full record

ArticleScientific reports2022

Role of TRPC6 in kidney damage after acute ischemic kidney injury.

Zhihuang Zheng, Dmitry Tsvetkov, Theda Ulrike Patricia Bartolomaeus, Cem Erdogan, Ute Krügel, Johanna Schleifenbaum, Michael Schaefer, Bernd Nürnberg, Xiaoning Chai, Friedrich-Alexander Ludwig and 5 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Zhihuang ZhengDepartment of Nephrology/Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Dmitry TsvetkovDepartment of Nephrology/Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany. dmitry.tsvetkov@charite.de.
Theda Ulrike Patricia BartolomaeusExperimental and Clinical Research Center (ECRC), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Charité Universitätsmedizin, Berlin, Germany.
Cem ErdoganInstitute of Vegetative Physiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Ute KrügelRudolf Boehm Institute for Pharmacology and Toxicology, Leipzig University, Leipzig, Germany.
Johanna SchleifenbaumInstitute of Vegetative Physiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Michael SchaeferRudolf Boehm Institute for Pharmacology and Toxicology, Leipzig University, Leipzig, Germany.
Bernd NürnbergDepartment of Pharmacology, Experimental Therapy and Toxicology and Interfaculty Center of Pharmacogenomics and Drug Research, University of Tübingen, Tübingen, Germany.
Xiaoning ChaiRudolf Boehm Institute for Pharmacology and Toxicology, Leipzig University, Leipzig, Germany.
Friedrich-Alexander LudwigDepartment of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig, Germany.
Gabriele N'diayeExperimental and Clinical Research Center (ECRC), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Charité Universitätsmedizin, Berlin, Germany.
May-Britt KöhlerExperimental and Clinical Research Center (ECRC), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Charité Universitätsmedizin, Berlin, Germany.
Kaiyin WuDepartment of Pathology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Maik GollaschDepartment of Nephrology/Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany. maik.gollasch@charite.de.
Lajos MarkóExperimental and Clinical Research Center (ECRC), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Charité Universitätsmedizin, Berlin, Germany. lajos.marko@charite.de.
Charité - Universitätsmedizin Berlin · DELeipzig University · DEMax Delbrück Center · DEGerman Centre for Cardiovascular Research · DEHelmholtz-Zentrum Dresden-Rossendorf · DEHumboldt-Universität zu Berlin · DEUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transient receptor potential channel subfamily C, member 6 (TRPC6), a non-selective cation channel that controls influx of Ca

Indexed as

Genetic VariationNegative ResultsAcute Kidney InjuryAnimalsAPACHECalciumIschemiaKidneyMice, TransgenicTRPC6 Cation ChannelCalciumTRPC6 Cation ChannelTrpc6 protein, mouse

Identifiers

PMID35194063
PMCPMC8864023
OpenAlexW4213452838

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.