Evidence map›Paper›PMID 35199479›Full record

ArticleJournal of diabetes investigation2022

Impact of diabetes on coronary physiology evaluated by quantitative flow ratio in patients who underwent percutaneous coronary intervention.

Zhen Ye, Qin Chen, Jiaxin Zhong, Long Chen, Lihua Chen, Mingfang Ye, Yuanming Yan, Lianglong Chen, Yukun Luo

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zhen YeDepartment of Cardiology, Fujian Medical University Union Hospital, Fuzhou, China.
Qin ChenDepartment of Cardiology, Fujian Medical University Union Hospital, Fuzhou, China.
Jiaxin ZhongDepartment of Cardiology, Fujian Medical University Union Hospital, Fuzhou, China.
Long ChenDepartment of Cardiology, Fujian Medical University Union Hospital, Fuzhou, China.
Lihua ChenDepartment of Cardiology, Fujian Medical University Union Hospital, Fuzhou, China.
Mingfang YeDepartment of Cardiology, Fujian Medical University Union Hospital, Fuzhou, China.
Yuanming YanDepartment of Cardiology, Fujian Medical University Union Hospital, Fuzhou, China.
Lianglong ChenDepartment of Cardiology, Fujian Medical University Union Hospital, Fuzhou, China.
Yukun LuoDepartment of Cardiology, Fujian Medical University Union Hospital, Fuzhou, China.ORCID https://orcid.org/0000-0002-9741-1687
Fujian Medical University · CN

Funding

Fujian Provincial Health Technology Project 2021GGB004Joint Funds for the Innovation of Science and Technology, Fujian Province 2020Y9098
6 · The paper itself

Abstract

AIMS/

introductionThere are mixed opinions on the influence of diabetes on the prognosis of patients receiving percutaneous coronary intervention (PCI). Therefore, in this study, the quantitative flow ratio (QFR), an emerging technology of functional evaluation, was used to explore the impact of diabetes on coronary physiology in patients who underwent PCI. MATERIALS AND

methodsPatients who underwent successful PCI and a 1-year angiographic follow up were retrospectively screened and analyzed by the QFR. Based on the presence or absence of diabetes, 677 enrolled patients (794 vessels) were classified into a diabetes group (211 patients, 261 vessels) and a non-diabetes group (466 patients, 533 vessels). The results of QFR analysis and clinical outcomes were compared between the two groups.

resultsThe two groups reached a similar level of post-PCI QFR (0.95 ± 0.09 vs 0.96 ± 0.06, P = 0.292). However, at the 1-year follow up, the QFR was lower (0.93 ± 0.11 vs 0.96 ± 0.07, P < 0.001), and the degree of QFR decline was more obvious (-0.024 ± 0.090 vs -0.008 ± 0.070, P = 0.023) in the diabetes group. Additionally, diabetes was independently associated with functional restenosis (odds ratio 2.164, 95% confidence interval 1.210-3.870, P = 0.009) and target vessel failure (odds ratio 2.654, 95% confidence interval 1.405-5.012, P = 0.003).

conclusionAs evaluated by the QFR, patients with diabetes received less coronary physiological benefit from PCI, which was consistent with their clinical outcomes.

Indexed as

Coronary Artery DiseaseDiabetes MellitusFractional Flow Reserve, MyocardialPercutaneous Coronary InterventionCoronary AngiographyCoronary VesselsHumansRetrospective StudiesDiabetesPercutaneous coronary interventionQuantitative flow ratio

Identifiers

PMID35199479
PMCPMC9248432
OpenAlexW4213451757

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.