Evidence map›Paper›PMID 35201574›Full record

ArticleHepatology international2022

Gender differences in the association of body composition and biopsy-proved nonalcoholic steatohepatitis.

Da Fang, Wenjuan Tang, Xiaoyu Zhao, Haixiang Sun, Tianwei Gu, Yan Bi

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In one paragraph

Article in Hepatology international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Da Fang *Department of Endocrinology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China.
Wenjuan Tang *Department of Endocrinology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Xiaoyu ZhaoDepartment of Endocrinology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Haixiang SunDepartment of Endocrinology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Tianwei GuDepartment of Endocrinology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China. gtw0235@163.com.
Yan BiDepartment of Endocrinology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China. biyan@nju.edu.cn.ORCID http://orcid.org/0000-0003-3914-7854
Nanjing Drum Tower Hospital · CN

Funding

Clinical Trials from the Affiliated Drum Tower Hospital, Medical School of Nanjing University 2021-LCYJ-DBZ-10National Natural Science Foundation of China 81770819National Natural Science Foundation of China 81800719National Natural Science Foundation of China 81800752National Natural Science Foundation of China 81900787National Natural Science Foundation of China 81970689National Natural Science Foundation of China 81970704National Natural Science Foundation of China 82000735National Natural Science Foundation of China 82000775National Natural Science Foundation of China 82030026National Natural Science Foundation of China 82070837Six Talent Peaks Project of Jiangsu Province of China YY-086
6 · The paper itself

Abstract

BACKGROUND AND

aimBody composition was associated with nonalcoholic steatohepatitis (NASH), but results were controversial probably due to gender differences. Hence, we aim to explore the association of body composition and NASH in males and females.

methodsWe conducted a cross-sectional analysis of obese subjects undergone liver biopsy. According to NASH Clinical Research Network system, subjects were categorized as Normal Control (NC), non-NASH or NASH. Body composition was accessed by dual-energy X-ray absorptiometry.

resultsThis study enrolled 336 subjects (mean age 32.0 years, mean BMI 39.15 kg/m

conclusionsWe firstly revealed that low RMM and high AGR were the independent risk factors for NASH in males and females, respectively, indicating that sex-specific interventions for improving body composition may reduce the risk of NASH in obese subjects.

Indexed as

Non-alcoholic Fatty Liver DiseaseAdultBiopsyBody CompositionCross-Sectional StudiesFemaleHumansLiverMaleObesitySex FactorsBody compositionFat distributionFat massHistologyLiver biopsyMuscle massNAFLD activity scoreNonalcoholic fatty liver diseaseNonalcoholic steatohepatitisObesity

Identifiers

PMID35201574
OpenAlexW4213421326

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.