Evidence map›Paper›PMID 35203261›Full record

ArticleCells2022

Calcineurin Controls Cellular Prion Protein Expression in Mouse Astrocytes.

Giulia Dematteis, Elena Restelli, Virginia Vita Vanella, Marcello Manfredi, Emilio Marengo, Marco Corazzari, Armando A Genazzani, Roberto Chiesa, Dmitry Lim, Laura Tapella

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Giulia DematteisDepartment of Pharmaceutical Sciences, Università del Piemonte Orientale "Amedeo Avogadro", 28100 Novara, Italy.
Elena RestelliDepartment of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.
Virginia Vita VanellaDepartment of Translational Medicine, Center for Translational Research on Autoimmune and Allergic Disease (CAAD), Università del Piemonte Orientale "Amedeo Avogadro", 28100 Novara, Italy.
Marcello ManfrediDepartment of Translational Medicine, Center for Translational Research on Autoimmune and Allergic Disease (CAAD), Università del Piemonte Orientale "Amedeo Avogadro", 28100 Novara, Italy.
Emilio MarengoDepartment of Sciences and Technological Innovation, Università del Piemonte Orientale "Amedeo Avogadro", 28100 Novara, Italy.ORCID 0000-0002-9395-7375
Marco CorazzariDepartment of Health Science (DSS), Center for Translational Research on Autoimmune and Allergic Disease (CAAD) & Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), Università del Piemonte Orientale "Amedeo Avogadro", 28100 Novara, Italy.ORCID 0000-0002-6246-5968
Armando A GenazzaniDepartment of Pharmaceutical Sciences, Università del Piemonte Orientale "Amedeo Avogadro", 28100 Novara, Italy.
Roberto ChiesaDepartment of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.ORCID 0000-0002-3842-3733
Dmitry LimDepartment of Pharmaceutical Sciences, Università del Piemonte Orientale "Amedeo Avogadro", 28100 Novara, Italy.ORCID 0000-0002-4316-2654
Laura TapellaDepartment of Pharmaceutical Sciences, Università del Piemonte Orientale "Amedeo Avogadro", 28100 Novara, Italy.ORCID 0000-0002-8159-1628
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITMario Negri Institute for Pharmacological Research · IT

Funding

Cassa Risparmio di Torino 1393-2017Fondazione Cariplo 2013-0795Fondazione Cariplo 2014-1094Università degli studi del Piemonte Orientale " Amedeo Avogadro" FAR 2016Università del Piemonte Orientale AGING Project-DIMETUniversità del Piemonte Orientale "Amedeo Avogadro" FAR 2019
6 · The paper itself

Abstract

Prion diseases arise from the conformational conversion of the cellular prion protein (PrP

Indexed as

Prion DiseasesPrionsAnimalsAstrocytesCalcineurinMicePrion ProteinsProteomicsCalcineurinPrion ProteinsPrionsastrocytescalcineurincalciumFK506neuroinflammationprion proteinprotein synthesis

Identifiers

PMID35203261
PMCPMC8870693
OpenAlexW4211263331

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.