ReviewBiology2022
Cognitive Impairment in Heart Failure-A Review.
Review in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 3 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Effects of Virtual Reality-Based Interventions for Promoting Physical Activity in Patients With Heart Failure: Systematic Review.Journal of medical Internet research · 2026Pooled it
- Prevalence and associated factors of cognitive frailty in older adults with heart failure: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Reprogramming heart failure: physiological orchestration and mechanistic decoding of exercise benefits.BMC cardiovascular disorders · 2025Pooled it
- Randomized comparison of the effects of tailored text messaging versus pillbox organizers on medication adherence of heart failure patients.BMC cardiovascular disorders · 2024Trial
- Cognitive assessment in heart failure: clinical value, timing, and practical tools.Heart failure reviews · 2026Review
- Exploring the Relationship Between Sleep Disturbances, Gut Microbiota, and Cognition in Patients with Heart Failure: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2026Article
- Cognition in Chronic Heart Failure: Advancing Knowledge for Better Prevention Through Remote Assessment.CJC open · 2026Article
- Alterations of Cerebral Extracellular Vesicle microRNA Profiling Potentially Disrupts Brain Homeostasis Following Myocardial Infarction.Biomolecules · 2026Article
- Article
- Overcoming Hyperkalaemia as a Barrier to Achieving Optimal RAASi Therapy and Cardiorenal Protection in Individuals with Cardiorenal Disease: A Podcast Discussion.Advances in therapy · 2026Article
- Analysis of a Real-World Population Participating in a Cardiac Rehabilitation Program: Cognitive Impairment, Functional Capacity, and Therapy Titration.Journal of clinical medicine · 2026Article
- Trajectory of cognitive decline before and after incident heart failure among older adults: A 20-Year, population-based, prospective cohort study.The journal of prevention of Alzheimer's disease · 2026Article
- Prognostic Impact of Combined Nutritional and Cognitive Status on Long-Term Outcome in Acute Decompensated Heart Failure.Nutrients · 2026Article
- Analysis of factors associated with cognitive impairment in elderly patients hospitalized with chronic heart failure.Frontiers in medicine · 2026Article
- Pediatric heart failure in the era of cardio-immunology: inflammatory-immune context phenotypes, diagnosis, and targeted management.Frontiers in immunology · 2026Review
- Association of Dementia With the Outcome of Patients With Heart Failure: Evidence From the Japanese KCHF Registry.Journal of the American Heart Association · 2025Observational
- A novel composite biomarker score for the identification of cognitive impairment in patients with heart failure: a pilot study.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals · 2025Article
- Heart Failure and Cognitive Impairment Through the Lens of the Gut Microbiome: A Narrative Review.Journal of personalized medicine · 2025Review
- Cognitive Safety and Outcomes of Pharmacological Management in Heart Failure: A Systematic Review.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Burden of cognitive impairment and its associated factors among patients with rheumatic heart disease at a tertiary cardiac center in Tanzania: A hospital-based cross-sectional study.Heart rhythm O2 · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Cognitive impairment (CI) is common in heart failure (HF). Patients with HF demonstrate reduced global cognition as well as deficits in multiple cognitive domains compared to controls. Degree of CI may be related to HF severity. HF has also been associated with an increased risk of dementia. Anatomical brain changes have been observed in patients with HF, including grey matter atrophy and increased white matter lesions. Patients with HF and CI have poorer functional independence and self-care, more frequent rehospitalisations as well as increased mortality. Pathophysiological pathways linking HF and CI have been proposed, including cerebral hypoperfusion and impaired cerebrovascular autoregulation, systemic inflammation, proteotoxicity and thromboembolic disease. However, these mechanisms are poorly understood. We conducted a search on MEDLINE, Embase and Scopus for original research exploring the connection between HF and CI. We then reviewed the relevant literature and discuss the associations between HF and CI, the patterns of brain injury in HF and their potential mechanisms, as well as the recognition and management of CI in patients with HF.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.