Evidence mapPaperPMID 35205347Full record

ReviewGenes2022

A Review on

Roozbeh Heidarzadehpilehrood, Maryam Pirhoushiaran, Rasoul Abdollahzadeh, Malina Binti Osman, Maryam Sakinah, Norshariza Nordin, Habibah Abdul Hamid

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
21.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.

  1. Pooled it
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  8. Binding Site Vectors Enable Mapping of Cytochrome P450 Functional Landscapes.Journal of chemical information and modeling · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Roozbeh HeidarzadehpilehroodDepartment of Obstetrics & Gynaecology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.ORCID 0000-0001-7420-0599
Maryam PirhoushiaranDepartment of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran 1417613151, Iran.
Rasoul AbdollahzadehDepartment of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran 1417613151, Iran.
Malina Binti OsmanDepartment of Medical Microbiology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.ORCID 0000-0001-5591-3315
Maryam SakinahDepartment of Obstetrics & Gynaecology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Norshariza NordinDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.ORCID 0000-0003-1019-0496
Habibah Abdul HamidDepartment of Obstetrics & Gynaecology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Universiti Putra Malaysia · MYTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polycystic ovary syndrome is a multifactorial condition associated with reproductive and endocrine organs and might cause infertility and metabolic abnormalities in childbearing age. PCOS seems to be a multifactorial disorder resulting from the combination of several genetic and environmental factors. Little research has been conducted to date on the impact of polymorphisms in infertility. We aim to review the appearance of polymorphisms in females of diverse ethnicities and their effect on infertility in the population with polycystic ovary syndrome. There have been numerous reports of the importance of the steroidogenesis pathway and genetic variants in PCOS pathogenesis. The most important genes that play a role in the aetiology of PCOS are

Indexed as

InfertilityPolycystic Ovary SyndromeAromataseCholesterol Side-Chain Cleavage EnzymeFemaleGenetic Predisposition to DiseaseHumansPolymorphism, GeneticSteroid 17-alpha-HydroxylaseAromataseCholesterol Side-Chain Cleavage EnzymeCYP17A1 protein, humanCYP19A1 protein, humanSteroid 17-alpha-Hydroxylasegenetic polymorphismhyperandrogenisminfertilityPCOSsteroidogenesis

Identifiers

PMID35205347
PMCPMC8871850
OpenAlexW4210314886

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.