Evidence map›Paper›PMID 35214749›Full record

ArticleVaccines2022

Neutralization of SARS-CoV-2 Variants by rVSV-ΔG-Spike-Elicited Human Sera.

Yfat Yahalom-Ronen, Noam Erez, Morly Fisher, Hadas Tamir, Boaz Politi, Hagit Achdout, Sharon Melamed, Itai Glinert, Shay Weiss, Inbar Cohen-Gihon and 14 more

Abstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. A comprehensive study of SARS-CoV-2 main protease (MbioRxiv : the preprint server for biology · 2023
    Article
  9. Article
  10. Antigen Delivery Systems: Past, Present, and Future.Biomolecules & therapeutics · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. SARS-CoV-2 3CLScience translational medicine · 2023
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Yfat Yahalom-RonenDepartment of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.
Noam ErezDepartment of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.ORCID 0000-0001-5241-8028
Morly FisherDepartment of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.
Hadas TamirDepartment of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.
Boaz PolitiDepartment of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.
Hagit AchdoutDepartment of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.ORCID 0000-0003-0664-8628
Sharon MelamedDepartment of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.
Itai GlinertDepartment of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.
Shay WeissDepartment of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.
Inbar Cohen-GihonDepartment of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.
Ofir IsraeliDepartment of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.ORCID 0000-0002-4590-6151
Marina IzakMagen David Adom, National Blood Services, Ramat Gan 52621, Israel.
Michal MandelboimSheba Medical Center, Central Virology Laboratory, Ministry of Health, Tel Hashomer, Ramat Gan 52621, Israel.
Yoseph CaracoHadassah Medical Center, Jerusalem 91120, Israel.
Noa Madar-BalakirskiDepartment of Pharmacology, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.
Adva MechalyDepartment of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.
Eilat ShinarMagen David Adom, National Blood Services, Ramat Gan 52621, Israel.
Ran ZichelDepartment of Biotechnology, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.ORCID 0000-0002-3249-4901
Daniel CohenSchool of Public Health, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.
Adi Beth-DinDepartment of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.ORCID 0000-0002-9602-2532
Anat ZviDepartment of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.
Hadar MarcusDepartment of Biotechnology, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.
Tomer IsraelyDepartment of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.ORCID 0000-0003-0246-4477
Nir ParanDepartment of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona 7410001, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of rapidly spreading variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a major challenge to the ability of vaccines and therapeutic antibodies to provide immunity. These variants contain mutations of specific amino acids that might impede vaccine efficacy. BriLife

Indexed as

BriLife®convalescentCOVID-19neutralizationSARS-CoV-2vaccinevariantsVOCVSV

Identifiers

PMID35214749
PMCPMC8879449

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.