Evidence map›Paper›PMID 35222374›Full record

ArticleFrontiers in immunology2022

IFN-β Deficiency Results in Fatal or Demyelinating Disease in C57BL/6 Mice Infected With Theiler's Murine Encephalomyelitis Viruses.

Melanie Bühler, Sandra Runft, Dandan Li, Jasper Götting, Claudia N Detje, Vanessa Nippold, Melanie Stoff, Andreas Beineke, Thomas Schulz, Ulrich Kalinke and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. When ISG15 is involved in inflammation.Frontiers in immunology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Melanie BühlerUniversity of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Sandra RunftUniversity of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Dandan LiUniversity of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Jasper GöttingInstitute of Virology, Hannover Medical School, Hannover, Germany.
Claudia N DetjeInstitute for Experimental Infection Research, Twincore, Centre for Experimental and Clinical Infection Research, a Joint Venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, Hannover, Germany.
Vanessa NippoldUniversity of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Melanie StoffUniversity of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Andreas BeinekeUniversity of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Thomas SchulzInstitute of Virology, Hannover Medical School, Hannover, Germany.
Ulrich KalinkeInstitute for Experimental Infection Research, Twincore, Centre for Experimental and Clinical Infection Research, a Joint Venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, Hannover, Germany.
Wolfgang BaumgärtnerUniversity of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Ingo GerhauserUniversity of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
University of Veterinary Medicine Hannover, Foundation · DEHelmholtz Centre for Infection Research · DEMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Demyelinating DiseasesEncephalomyelitisTheilovirusAnimalsInterferon-betaInterferon-gammaMiceMice, Inbred C57BLRNA, MessengerInterferon-betaInterferon-gammaRNA, MessengerdemyelinationencephalitisIFN-βimmunohistochemistryknockout miceRT-qPCRTMEV strains

Identifiers

PMID35222374
PMCPMC8864290
OpenAlexW4210824658

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.