ReviewThe Journal of international medical research2022
Potential relationships between COVID-19 and the thyroid gland: an update.
Review in The Journal of international medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 3 syntheses or guidelines pooled it, 71 citations in OpenAlex.
- Thyroid function during COVID-19 and post-COVID complications in adults: a systematic review.Frontiers in endocrinology · 2024Pooled it
- Pooled it
- Association of thyroid dysfunction and COVID-19: A systematic review and meta-analysis.Frontiers in endocrinology · 2022Pooled it
- Long-Term Thyroid Complications Post-COVID-19: A Systematic Review.Microorganisms · 2026Review
- COVID-19 pandemic and thyroid diseases.Frontiers in endocrinology · 2026Article
- Long-term risk of incident thyroid cancer after COVID-19 in patients with thyroid disorder: a multicenter propensity score-matched cohort study.Frontiers in endocrinology · 2026Article
- Post-COVID-19 Painless Thyroiditis: A Case Study on Thyrotoxicosis Management.The American journal of case reports · 2025Article
- Non-Thyroidal Illness Syndrome and Thyroid Autoimmunity in Hospitalized COVID-19 Patients: A Retrospective Study.Journal of clinical medicine · 2025Article
- Association Between COVID-19 Infection and Thyroid Cancer Development: A Retrospective Cohort Study Using the TriNetX Database.Biomedicines · 2025Article
- Gene behaviors-based network enrichment analysis and its application to reveal immune disease pathways enriched with COVID-19 severity-specific gene networks.Bioinformatics (Oxford, England) · 2025Article
- Assessing the Causal Association Between COVID-19 and Graves Disease: Mendelian Randomization Study.JMIR formative research · 2025Article
- A 6-Year Retrospective Study in Surgery Patients with Thyroid Diseases in Mureș County, Romania, Before and During the COVID-19 Pandemic.Diagnostics (Basel, Switzerland) · 2025Article
- Clinical characteristics of Graves' disease following COVID-19 infection or vaccination: a multicenter case-control study.Turkish journal of medical sciences · 2025Article
- Article
- Finding Long-COVID: temporal topic modeling of electronic health records from the N3C and RECOVER programs.NPJ digital medicine · 2024Article
- Review
- Comparative analysis of clinical profile, laboratory profile and outcome in COVID-19 patients with and without hypothyroidism.Ghana medical journal · 2024Observational
- Finding Long-COVID: Temporal Topic Modeling of Electronic Health Records from the N3C and RECOVER Programs.medRxiv : the preprint server for health sciences · 2024Article
- Impact of COVID-19 pandemic on thyroidectomy for malignant diseases in high-volume referral centers.Updates in surgery · 2024Article
- Papillary Thyroid Cancer Trends in the Wake of the COVID-19 Pandemic: Is There a Shift toward a More Aggressive Entity?Diseases (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this review, I aim to provide a complete overview of recent advances in knowledge regarding severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2)-induced thyroid dysfunction. I discuss the findings regarding the role of SARS-CoV-2 in the development of thyroid dysfunction, including subacute thyroiditis, Graves' disease, non-thyroidal illness, thyrotoxicosis and Hashimoto's thyroiditis during and subsequent to coronavirus disease 2019 (COVID-19). The thyroid gland and the entire hypothalamic-pituitary-thyroid (HPT) axis may represent key targets of SARS-CoV-2. Thyroid dysfunction during and subsequent to COVID-19 has been documented in clinical studies and is usually reversible. Most of the thyroid disorders, including Graves' disease, euthyroid sick syndrome, Hashimoto's thyroiditis and subacute thyroiditis, have been documented as sequelae to COVID-19, and the SARS-CoV-2 virus has been implicated in the aetiology of each. COVID-19 has been suggested to trigger the activation of pre-existing thyroid disease or autoimmunity. Furthermore, patients with uncontrolled thyrotoxicosis are at risk of SARS-CoV-2 infection-related consequences. Because of the neutropenia caused by antithyroid medications, which may obscure the signs of COVID-19, this group of patients should receive special attention. It is suggested that thyroid dysfunction during COVID-19 is caused by direct infection of the thyroid or "cytokine storm"-mediated autoimmune effects on the thyroid.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.