Evidence map›Paper›PMID 35227342›Full record

Trial reportPsychological medicine2023

Efficacy of a transdiagnostic, prevention-focused program for at-risk young adults: a waitlist-controlled trial.

Nicole R DeTore, Lauren Luther, Wisteria Deng, Jordan Zimmerman, Logan Leathem, Anne S Burke, Maren B Nyer, Daphne J Holt

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Article
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  9. Review
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  11. Transdiagnostic prevention in youth mental health, Part I: rationale, shared risk factors.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  12. Transdiagnostic prevention in youth mental health, Part II: interventions.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nicole R DeToreDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.ORCID https://orcid.org/0000-0002-4714-1973
Lauren LutherDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Wisteria DengDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Jordan ZimmermanDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Logan LeathemUniversity of California, Los Angeles, CA, USA.
Anne S BurkeDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Maren B NyerDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Daphne J HoltDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.ORCID https://orcid.org/0000-0002-6428-9603

Funding

Doctoral Training in Brain and Behavioral Development During Adolescence (UCLA BBDA)T32HD091059 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Mirella Dapretto, ANDREW J FULIGNI · 2018 to 2026
$1.7M
NICHD NIH HHS T32 HD091059
6 · The paper itself

Abstract

backgroundPrevention programs that are 'transdiagnostic' may be more cost-effective and beneficial, in terms of reducing levels of psychopathology in the general population, than those focused on a specific disorder. This randomized controlled study evaluated the efficacy of one such intervention program called Resilience Training (RT).

methodsCollege students who reported mildly elevated depressive or subclinical psychotic symptoms ('psychotic experiences' (PEs)) (

resultsCompared to the waitlist control group, RT participants reported significantly greater reductions in PEs, distress associated with PEs, depression, and anxiety, as well as significantly greater improvements in resilience, mindfulness, self-compassion, and positive affect, following the 4-week RT/waitlist period (all

conclusionsRT is a brief, group-based intervention associated with improved resilience and reduced symptoms of psychopathology, with sustained effects on PEs, in transdiagnostically at-risk young adults. Follow-up studies can further assess the efficacy of RT relative to other interventions and test whether it can reduce the likelihood of developing a serious mental illness.

Indexed as

AnxietyPsychotic DisordersAnxiety DisordersFollow-Up StudiesHumansStudentsYoung AdultAt-risk youthdepressionmindfulnesspreventionpsychotic experiencesresilienceself-compassiontransdiagnostic

Identifiers

PMID35227342
PMCPMC9433469

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.