Evidence map›Paper›PMID 35228260›Full record

ArticleLife science alliance2022

Growth-rate-dependent and nutrient-specific gene expression resource allocation in fission yeast.

Istvan T Kleijn, Amalia Martínez-Segura, François Bertaux, Malika Saint, Holger Kramer, Vahid Shahrezaei, Samuel Marguerat

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life science alliance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Istvan T KleijnMedical Research Council London Institute of Medical Sciences (MRC LMS), London, UK.ORCID 0000-0001-9466-9167
Amalia Martínez-SeguraMedical Research Council London Institute of Medical Sciences (MRC LMS), London, UK.
François BertauxMedical Research Council London Institute of Medical Sciences (MRC LMS), London, UK.ORCID 0000-0002-0942-6142
Malika SaintMedical Research Council London Institute of Medical Sciences (MRC LMS), London, UK.ORCID 0000-0001-7509-0619
Holger KramerMedical Research Council London Institute of Medical Sciences (MRC LMS), London, UK.ORCID 0000-0002-6400-0945
Vahid ShahrezaeiDepartment of Mathematics, Faculty of Natural Sciences, Imperial College London, London, UK v.shahrezaei@imperial.ac.uk.ORCID 0000-0002-4013-5458
Samuel MargueratMedical Research Council London Institute of Medical Sciences (MRC LMS), London, UK samuel.marguerat@ucl.ac.uk.ORCID 0000-0002-2402-3165
MRC London Institute of Medical Sciences · GBImperial College London · GB

Funding

Medical Research Council MC_UP_1102/8Wellcome Trust
6 · The paper itself

Abstract

Cellular resources are limited and their relative allocation to gene expression programmes determines physiological states and global properties such as the growth rate. Here, we determined the importance of the growth rate in explaining relative changes in protein and mRNA levels in the simple eukaryote

Indexed as

SchizosaccharomycesSchizosaccharomyces pombe ProteinsGene Expression Regulation, FungalNutrientsProteomeTranscriptomeNutrientsProteomeSchizosaccharomyces pombe Proteins

Identifiers

PMID35228260
PMCPMC8886410
OpenAlexW4220749815

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.