Evidence map›Paper›PMID 35234162›Full record

ArticleJournal of musculoskeletal & neuronal interactions2022

Rehabilitation outcomes in Huntington disease patients with low body mass index.

Irene Ciancarelli, Giovanni Morone, Marco Iosa, Stefano Paolucci, Loris Pignolo, Paolo Tonin, Antonio Cerasa, Maria Giuliana Tozzi Ciancarelli

Abstract read
In one paragraph

Article in Journal of musculoskeletal & neuronal interactions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Irene CiancarelliDepartment of Life, Health and Environmental Sciences, University of L'Aquila - 67100 L'Aquila - Italy.
Giovanni MoroneSanta Lucia Foundation IRCCS, Rome, Italy.
Marco IosaSanta Lucia Foundation IRCCS, Rome, Italy.
Stefano PaolucciSanta Lucia Foundation IRCCS, Rome, Italy.
Loris PignoloS. Anna Rehabilitation Institute, RAN - Research on Advanced Neurorehabilitation, Italy.
Paolo ToninS. Anna Rehabilitation Institute, RAN - Research on Advanced Neurorehabilitation, Italy.
Antonio CerasaS. Anna Rehabilitation Institute, RAN - Research on Advanced Neurorehabilitation, Italy.
Maria Giuliana Tozzi CiancarelliDepartment of Life, Health and Environmental Sciences, University of L'Aquila - 67100 L'Aquila - Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesA catabolic state and a progressive body weight loss are a well-documented hallmark of Huntington Disease (HD). No study is still available on the effectiveness of intensive in-hospital rehabilitation in HD patients with low body mass index (BMI).

methodsTwenty HD patients with low BMI value were enrolled in this study. Disease severity was assessed before and after rehabilitation by the Barthel Index, the Total Functional Capacity Scale, and the Physical Performance Test.

resultsBMI-scores correlated with clinical measures before and after rehabilitation. All patients showed an improvement in outcome measures (p<0.001), and an increase in BMI values (p<0.001) after rehabilitation. Effectiveness of rehabilitation correlated with the values of BMI assessed before reheducational programs (p=0.024) and with BMI values observed in each patient in the three months before admission to hospital (p=0.002).

conclusionsFindings of the current study show that the effectiveness of the rehabilitation is positively correlated with the BMI values and confirm the efficacy of in-hospital intensive rehabilitation as a valid strategy finalized to improve neuromotor performances and global functional recovery even in HD patients with low BMI and at risk of malnutrition.

Indexed as

Huntington DiseaseBody Mass IndexHumansRecovery of FunctionTreatment OutcomeWeight LossBody Mass IndexHuntington DiseaseNutritional statusRehabilitation

Identifiers

PMID35234162
PMCPMC8919652

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.