Evidence map›Paper›PMID 35237643›Full record

ArticleFrontiers in nutrition2022

Endothelial Progenitor Cell Levels and Extent of Post-prandial Lipemic Response.

Buket Akcan, Asim Örem, Yahya Altinkaynak, Birgül Kural, Cihan Örem, Mehmet Sönmez, Mauro Serafini

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Buket AkcanDepartment of Nutrition and Dietetics, Faculty of Health, Ardahan University, Ardahan, Turkey.
Asim ÖremDepartment of Medical Biochemistry, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Yahya AltinkaynakDepartment of Medical Services and Techniques, Ardahan Vocational School of Health Services, Ardahan University, Ardahan, Turkey.
Birgül KuralDepartment of Medical Biochemistry, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Cihan ÖremDepartment of Cardiology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Mehmet SönmezDepartment of Hematology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Mauro SerafiniFunctional Food and Metabolic Stress Prevention Laboratory, Teramo University, Teramo, Italy.
Karadeniz Technical University · TRArdahan University · TRUniversity of Teramo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveDue to the frequency of meal ingestion, individuals spend the majority of the day, ~18 h, in a status of post-prandial (PP) stress. Remnant-like lipoprotein particles (RLPs) are predominant in PP phase playing an important role in the development of atherosclerosis. Endothelial progenitor cells (EPCs) have been suggested to play a role in vessel wall homeostasis and in reducing atherosclerosis. However, there is no information about peripheral blood EPCs number following PP stress. We investigated the association between circulating EPCs levels and extent of PP lipemia in healthy subjects following a high-fat meal. MATERIALS AND

methodsA total of 84 healthy subjects (42 men, 42 women) aged 17-55 years were included in the study. PP lipemic response of subjects was determined by Oral Fat-Loading Test (OFLT). All the subjects were classified on the basis of their plasma TG levels after PP lipemic stressors in categories 1 (low), 2 (moderate), and 3 (high). Circulating EPCs numbers were measured by the flow cytometry method.

resultsThere was a significant difference in terms of lipid parameters between men and women: high-density lipoprotein cholesterol (HDL-C) was significantly lower in men than in women (

conclusionIncreased EPCs levels in subjects with different PP hyperlipidemia may be associated with a response to endothelial injury, related to increased atherogenic remnant particles at the PP phase.

Indexed as

atherosclerosisendothelial injuryhigh fat diethyperlipidemiaremnant-like lipoproteins

Identifiers

PMID35237643
PMCPMC8885282
OpenAlexW4212960642

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.