ArticleJournal of bone and mineral metabolism2022
Relationship between oseteoporosis with fatty infiltration of paraspinal muscles based on QCT examination.
Article in Journal of bone and mineral metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Fatty infiltration and cross-sectional area as indicators of muscle mass in osteoporosis: a meta-regression study.Frontiers in endocrinology · 2025Pooled it
- The value of radiomics to predict abnormal bone mass in type 2 diabetes mellitus patients based on CT imaging for paravertebral muscles.Frontiers in endocrinology · 2022Trial
- Intramuscular fat infiltration is associated with higher vertebral void space burden and lower volumetric bone mineral density in older adults.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Diagnostic Perspectives on the Relationship Between Paraspinal Muscles and Bone Mineral Density: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Relation of bone mineral density with fat infiltration of paraspinal muscles.Osteoporosis and sarcopenia · 2025Article
- Associations between abdominal fat, psoas muscle fat, and lumbar spine bone density: insights from quantitative CT imaging.BMC musculoskeletal disorders · 2025Article
- Variations of QCT-based abdominal and paravertebral muscle tissue content by age and gender.BMC musculoskeletal disorders · 2025Article
- Identifying gut microbiotaFrontiers in microbiology · 2025Article
- Clinical use of quantitative computed tomography to evaluate the effect of less paraspinal muscle damage on bone mineral density changes after lumbar interbody fusion.Asian spine journal · 2024Article
- Relationship between paraspinal muscle properties and bone mineral density based on QCT in patients with lumbar disc herniation.BMC musculoskeletal disorders · 2024Article
- Vitamin D in Osteosarcopenic Obesity.Nutrients · 2022Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
introductionTo investigate the correlation between paraspinal muscles features and osteoporosis in lumbar spine. MATERIALS AND
methodsA total of 367 subjects who underwent quantitative computed tomography (QCT) examination were enrolled in this study. QCT pro workstation was used to obtain the mean bone mineral density (BMD) of the lower lumbar spine. Fat fraction (FF) and cross-section area (CSA) of the paraspinal muscles at the corresponding levels were measured. All participants were divided into normal, osteopenia, and osteoporosis groups. One-way ANOVA and independent samples t tests were performed to compare differences between groups. Pearson and Spearman correlation coefficients and partial correlation analysis after controlling for confounding factors were used to analyze the correlation between BMD and paraspinal muscles measurements.
resultsAmong the 367 participants included, 116 were in the normal group, 130 in the osteopenia group and 121 in the osteoporosis group. There were significant differences among the three groups for the mean and multifidus FF. BMD showed negative correlations with the FF of the paraspinal muscles. Multifidus and mean FF showed the best correlation (r = - 0.654, - 0.777). There were also significant differences in the mean and multifidus FF between different age groups, while after controlling for confounding factors, there was no correlation between age and FF of the paraspinal muscles.
conclusionThis preliminary study demonstrated the association of BMD with fatty infiltration of paraspinal muscles. Different muscles might have specific effects in different sex and age groups.
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Registered trials
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