Evidence map›Paper›PMID 35239107›Full record

ReviewCurrent rheumatology reports2022

Expanding Roles of Noncoding RNAs in the Pathogenesis of Systemic Lupus Erythematosus.

Yiwei Shen, Bo Qu, Nan Shen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current rheumatology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Long Non-Coding RNAJournal of inflammation research · 2025
    Article
  2. Crosstalk of ubiquitin system and non-coding RNA in fibrosis.International journal of biological sciences · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yiwei ShenDepartment of Rheumatology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Shandong Middle Road, Shanghai, 200001, China.
Bo QuDepartment of Rheumatology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Shandong Middle Road, Shanghai, 200001, China.
Nan ShenDepartment of Rheumatology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Shandong Middle Road, Shanghai, 200001, China. Nan.Shen@cchmc.org.
Shanghai Jiao Tong University · CN

Funding

Futian Healthcare Research Project FTWS2021006National Human Genetic Resources Sharing Service Platform 2005DKA21300National Natural Science Foundation of China 31630021National Natural Science Foundation of China 31930037National Natural Science Foundation of China 81102266Sanming Project of Medicine in Shenzhen SZSM201602087Shanghai Clinical Research Center for Rheumatism and Immune Diseases 20MC1920300Shanghai Municipal Key Medical Center Construction Project 2017ZZ01024-002Shenzhen Science and Technology Project JCYJ20180504170414637
6 · The paper itself

Abstract

purpose of reviewThe exact pathogenesis of systemic lupus erythematosus (SLE) remains unclear. Accumulating finds have indicated the roles of the non-coding RNAs (ncRNAs) acting as novel epigenetic regulatory elements in the dysfunction of the immune system in SLE. This review will introduce recent studies on how ncRNAs are involved in the development of SLE. RECENT

findingsRecent advances in ncRNAs biology have greatly expanded our understanding of epigenetic regulation of immune responses and inflammation, and increasing evidence suggests ncRNAs are important players in SLE development. Identifications of abnormal expression patterns of ncRNAs and relevant biological impacts in lupus patients have revealed their potential as novel biomarkers and therapeutic targets for SLE. The dysregulation of ncRNAs contributes to the immunopathogenesis of SLE. Clarifying the functions and mechanisms of SLE-associated ncRNAs provides new opportunities for disease biomarkers and targeted therapies.

Indexed as

Epigenesis, GeneticLupus Erythematosus, SystemicBiomarkersHumansRNA, UntranslatedBiomarkersRNA, UntranslatedImmune responseLupus nephritisNon-coding RNAPathogenesisSystemic lupus erythematosus

Identifiers

PMID35239107
OpenAlexW4214908435

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.