Evidence map›Paper›PMID 35240358›Full record

ArticlePoultry science2022

A blend of microencapsulated organic acids and botanicals reduces necrotic enteritis via specific signaling pathways in broilers.

Christina L Swaggerty, J Allen Byrd, Ryan J Arsenault, Famatta Perry, Casey N Johnson, Kenneth J Genovese, Haiqi He, Michael H Kogut, Andrea Piva, Ester Grilli

Open access · goldAbstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in Poultry science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Big Data and AI-Powered Modeling: A Pathway to Sustainable Precision Animal Nutrition.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  5. Article
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  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Christina L SwaggertyU.S. Department of Agriculture, Agricultural Research Service, Southern Plains Agricultural Research Center, College Station, TX 77845, USA. Electronic address: christi.swaggerty@usda.gov.
J Allen ByrdU.S. Department of Agriculture, Agricultural Research Service, Southern Plains Agricultural Research Center, College Station, TX 77845, USA.
Ryan J ArsenaultDepartment of Animal and Food Sciences, University of Delaware, Newark, DE, USA.
Famatta PerryDepartment of Animal and Food Sciences, University of Delaware, Newark, DE, USA.
Casey N JohnsonDepartment of Animal and Food Sciences, University of Delaware, Newark, DE, USA.
Kenneth J GenoveseU.S. Department of Agriculture, Agricultural Research Service, Southern Plains Agricultural Research Center, College Station, TX 77845, USA.
Haiqi HeU.S. Department of Agriculture, Agricultural Research Service, Southern Plains Agricultural Research Center, College Station, TX 77845, USA.
Michael H KogutU.S. Department of Agriculture, Agricultural Research Service, Southern Plains Agricultural Research Center, College Station, TX 77845, USA.
Andrea PivaDIMEVET, University of Bologna, Ozzano Emilia, Bologna, Italy; Vetagro S.p.A., Reggio Emilia, Italy.
Ester GrilliDIMEVET, University of Bologna, Ozzano Emilia, Bologna, Italy; Vetagro Inc., Chicago, IL, USA.
Agricultural Research Service · USUniversity of Delaware · USUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Necrotic enteritis (NE) is a devastating disease that has seen a resurgence of cases following the removal of antibiotics from feed resulting in financial loss and significant animal health concerns across the poultry industry. The objective was to evaluate the efficacy of a microencapsulated blend of organic (25% citric and 16.7% sorbic) acids and botanicals (1.7% thymol and 1% vanillin [AviPlusP]) to reduce clinical NE and determine the signaling pathways associated with any changes. Day-of-hatch by-product broiler breeder chicks were randomly assigned to a control (0) or supplemented (500 g/MT) diet (n = 23-26) and evaluated in a NE challenge model (n = 3). Birds were administered 2X cocci vaccine on d 14 and challenged with a cocktail of Clostridium perfringens strains (10

Indexed as

Clostridium InfectionsEnteritisPoultry DiseasesAcidsAnimal FeedAnimalsChickensClostridium perfringensDietNecrosisOrganic ChemicalsSignal TransductionAcidsOrganic ChemicalsClostridium perfringensfeed additive, kinome, microencapsulated organic acids and botanicals, necrotic enteritis

Identifiers

PMID35240358
PMCPMC8892003
OpenAlexW4210630591

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.