ArticleScientific reports2022
The association between the non-HDL-cholesterol to HDL-cholesterol ratio and 28-day mortality in sepsis patients: a cohort study.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Association between adverse childhood experiences and accelerated aging of middle-aged and older Chinese: based on the China health and retirement longitudinal study.BMC public health · 2026Observational
- Macrophage metabolism reprogramming in sepsis: Pathogenesis and therapeutic implications (Review).International journal of molecular medicine · 2026Review
- J-shaped association between serum bicarbonate and 28-day ICU mortality in adult patients with sepsis: A multicenter cohort analysis.Medicine · 2026Article
- Article
- The Impact of the CALLY Index on All-Cause Mortality in Patients With Depression: A Longitudinal Analysis Using NHANES Data.Health science reports · 2026Article
- A nonlinear association and threshold effect of healthy eating index-2015 with hypertension in US children and adolescents: a cross-sectional analysis of NHANES 1999-2020.Journal of health, population, and nutrition · 2026Article
- Non-HDL to HDL cholesterol ratio and coronary outcomes in U.S. adults: a cross-sectional and prospective NHANES analysis.European journal of medical research · 2026Article
- Overreactive parenting links maternal depressive symptoms and child prosocial behaviors among mother-child dyads in Western China.BMC public health · 2026Article
- Nonlinear associations between maternal depressive symptoms and children's mental health: a cross-sectional study.BMC psychology · 2026Article
- Telomere length in leukocyte as biomarker for diagnosis of primary Sjögren's syndrome: a cross-sectional study.Clinical rheumatology · 2026Article
- Association between atherogenic index of plasma and ICU 28-day mortality in geriatric diabetes: an EICU-based retrospective analysis.Lipids in health and disease · 2025Article
- The non-linear association between depression scores and all-cause mortality: a cohort study based on NHANES 2005-2018 data.Scientific reports · 2025Article
- Nonlinear relationship between triglyceride-glucose index and cardiovascular mortality with competing risk analysis on populations aged 18-80 years.BMC cardiovascular disorders · 2025Article
- Association between lactate-albumin ratio and 28-day mortality in patients with sepsis-associated acute kidney injury: a retrospective cohort study.Scientific reports · 2025Article
- The lean body mass to visceral fat mass ratio is negatively associated with cardiometabolic disorders: a cross-sectional study.Scientific reports · 2025Article
- Beyond traditional metrics: evaluating the triglyceride-total cholesterol-body weight index (TCBI) in cardiovascular risk assessment.BMC cardiovascular disorders · 2025Article
- Association of mean corpuscular volume with 28-day mortality in sepsis patients: A retrospective cohort study using eICU data.PloS one · 2025Article
- Prognostic value of glycolipid metabolism index on complications and mechanical ventilation in intensive care unit patients with intracerebral hemorrhage: a retrospective cohort study using the MIMIC-IV database.Frontiers in neurology · 2025Article
- Non-linear association between lactate and 28 days mortality in elderly patients with sepsis across different SOFA score groups: results from the eICU Collaborative Research Database.Frontiers in medicine · 2025Article
- Article
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Abstract
The focus of this study was to explore the association between the non-HDL-cholesterol to HDL-cholesterol (non-HDLc/HDLc) ratio and mortality in septic patients. This was a retrospective cohort study of patients with sepsis in the eICU Collaborative Research Database (eICU-CRD) from 208 distinct ICUs across the United States between 2014 and 2015 that explored. All-cause mortality within 28 days after ICU admission. A multivariable logistic regression model was used to estimate the risk of death. Of the 724 patients with a median age of 68 years, 43 (5.94%) died within 28 days after ICU admission. When the non-HDLc/HDLc ratio was < 3.3, the mortality rate decreased with an adjusted odds ratio (OR) of 0.60 (95% CI 0.37-0.99, P = 0.043) for every 1 increment in the non-HDLc/HDLc ratio. When the non-HDLc/HDLc ratio was ≥ 3.3, the mortality rate increased with an adjusted OR of 1.28 (95% CI 1.01-1.62, P = 0.039) for every one increment in the non-HDLc/HDLc ratio. For patients with sepsis, the association between the non-HDLc/HDLc ratio and the 28-day mortality risk was a U-shaped curve. A higher or lower non-HDLc/HDLc ratio was associated with an increased risk of 28-day mortality.
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