Evidence map›Paper›PMID 35249367›Full record

ArticleJournal of clinical microbiology2022

Evaluation of Rezafungin Provisional CLSI Clinical Breakpoints and Epidemiological Cutoff Values Tested against a Worldwide Collection of Contemporaneous Invasive Fungal Isolates (2019 to 2020).

Cecilia G Carvalhaes, Abby L Klauer, Paul R Rhomberg, Michael A Pfaller, Mariana Castanheira

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Outcomes byAntimicrobial agents and chemotherapy · 2024
    Trial
  3. Article
  4. Article
  5. Article
  6. Genomic Insights ofOpen forum infectious diseases · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Activity of Rezafungin Against Echinocandin Non-wild typeOpen forum infectious diseases · 2025
    Article
  11. Article
  12. Anidulafungin is a useful surrogate marker for predictingJournal of clinical microbiology · 2025
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Necrotizing gingival infection due toTherapeutic advances in infectious disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cecilia G CarvalhaesJMI Laboratoriesgrid.419652.d, North Liberty, Iowa, USA.ORCID 0000-0002-2734-3754
Abby L KlauerJMI Laboratoriesgrid.419652.d, North Liberty, Iowa, USA.ORCID 0000-0002-9881-8286
Paul R RhombergJMI Laboratoriesgrid.419652.d, North Liberty, Iowa, USA.ORCID 0000-0001-6798-7653
Michael A PfallerJMI Laboratoriesgrid.419652.d, North Liberty, Iowa, USA.ORCID 0000-0003-4501-6068
Mariana CastanheiraJMI Laboratoriesgrid.419652.d, North Liberty, Iowa, USA.ORCID 0000-0003-0126-1782
JMI Laboratories · US

Funding

Cidara Therapeutics 21-CID-04
6 · The paper itself

Abstract

Rezafungin is a new echinocandin under development for the treatment of candidemia and invasive candidiasis. CLSI recently approved provisional susceptible-only breakpoints and epidemiological cutoff values for

Indexed as

Antifungal AgentsCandidiasis, InvasiveAspergillusCandida glabrataCandida parapsilosisDrug Resistance, FungalEchinocandinsFluconazoleHumansMicrobial Sensitivity TestsAntifungal AgentsEchinocandinsFluconazoleRezafunginA. fumigatusantifungalAspergillusC. albicansCandidaechinocandin

Identifiers

PMID35249367
PMCPMC9020363
OpenAlexW4220993687

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.