Evidence map›Paper›PMID 35251480›Full record

ArticleOxidative medicine and cellular longevity2022

Glaucocalyxin B Attenuates Ovarian Cancer Cell Growth and Cisplatin Resistance In Vitro via Activating Oxidative Stress.

Tingting Zhang, Chenxin Xu, Peisen Zheng, Xiaoxian Zhang, Chenyu Qiu, Fengjiao Wu, Jundixia Chen, Zhongxiang Xiao, Jiandong Zhu, Jingjing Zhang and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Tingting ZhangAffiliated Yueqing Hospital, Wenzhou Medical University, Wenzhou 325035, China.
Chenxin XuSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
Peisen ZhengSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
Xiaoxian ZhangSchool of Nursing, Wenzhou Medical University, Wenzhou 325035, China.
Chenyu QiuSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
Fengjiao WuSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
Jundixia ChenAffiliated Yueqing Hospital, Wenzhou Medical University, Wenzhou 325035, China.
Zhongxiang XiaoAffiliated Yueqing Hospital, Wenzhou Medical University, Wenzhou 325035, China.
Jiandong ZhuAffiliated Yueqing Hospital, Wenzhou Medical University, Wenzhou 325035, China.
Jingjing ZhangSchool of Nursing, Wenzhou Medical University, Wenzhou 325035, China.
Peng ZouAffiliated Yueqing Hospital, Wenzhou Medical University, Wenzhou 325035, China.ORCID https://orcid.org/0000-0001-5105-834X
Daoyong NiAffiliated Yueqing Hospital, Wenzhou Medical University, Wenzhou 325035, China.ORCID https://orcid.org/0000-0003-4790-5985
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer is one of the fatal gynecological cancers around the world. Cisplatin is the first-line chemotherapy drug for the clinical treatment of ovarian cancer. However, many patients with ovarian cancer are still suffering from resistance to cisplatin. Therefore, the new drug combinations or treatment strategies for ovarian cancer are urgently needed. Glaucocalyxin B (GLB), a diterpenoid isolated from the aerial parts of

Indexed as

Antineoplastic AgentsCell Line, TumorCell ProliferationCell SurvivalCisplatinDiterpenes, KauraneDNA DamageDrug Resistance, NeoplasmDrug SynergismFemaleHumansIsodonJNK Mitogen-Activated Protein KinasesMAP Kinase Signaling SystemOvarian NeoplasmsOxidative StressAntineoplastic AgentsCisplatinDiterpenes, Kauraneglaucocalyxin BJNK Mitogen-Activated Protein KinasesPhytochemicalsPlant ExtractsReactive Oxygen Species

Identifiers

PMID35251480
PMCPMC8896941
OpenAlexW4214623782

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.