ReviewFrontiers in nutrition2022
The Interplay of Obesity, Dyslipidemia and Immune Dysfunction: A Brief Overview on Pathophysiology, Animal Models, and Nutritional Modulation.
Review in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Exploring the Effects of Short-Term Daily Intake ofNutrients · 2023Trial
- The Mediating Role of Normal Triglyceride Levels on Lymphocyte Populations in Abdominal Obesity: A Cross-Sectional Study.Health science reports · 2026Article
- The Effects and Mechanisms of Pomegranate on Regulating Lipid Metabolism.Food science & nutrition · 2026Article
- C-Reactive Protein and Neurological Autoimmune Diseases: Bridging the Diagnostic and Pathogenic Gap.International journal of molecular sciences · 2026Review
- What affects natural killer cell activity: a cross-sectional study.Frontiers in immunology · 2026Article
- Impact of anti-peptic ulcer disease (PUD) medications on hyperlipidemia risk in patients with PUD: a population-based retrospective cohort study.Therapeutic advances in endocrinology and metabolism · 2026Article
- Capsaicin and Its Combination with Oleic Acid Affect Membrane Fatty Acid Remodeling and Cytokine-Chemokine Secretion in HepG2 Cells.International journal of molecular sciences · 2025Article
- Article
- Navigating Cardiovascular Challenges of Obesity: Exploring Preventive Approaches.Endocrine, metabolic & immune disorders drug targets · 2025Review
- Double Diabetes: A Clinical Challenge.Clinical diabetes : a publication of the American Diabetes Association · 2025Article
- Association Between CTLA4 Level and Obesity, Dyslipidemia, and Type 2 Diabetes Mellitus.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2025Article
- Article
- Plant- and Animal-Derived Dietary Sources of Phosphatidylcholine Have Differential Effects on Immune Function in The Context of A High-Fat Diet in Male Wistar Rats.The Journal of nutrition · 2024Article
- The Effects of Antioxidant Supplementation on the Pathologic Mechanisms of Metabolic Syndrome and Cardiovascular Disease Development.Nutrients · 2024Review
- Effects of dietary fibre on metabolic health and obesity.Nature reviews. Gastroenterology & hepatology · 2024Review
- Article
- Identification of hub genes associated withWorld journal of diabetes · 2024Article
- Ecological change of the gut microbiota during pregnancy and progression to dyslipidemia.NPJ biofilms and microbiomes · 2023Article
- Dietary Supplement, Containing the Dry Extract ofMetabolites · 2023Article
- Low-fat dairy consumption improves intestinal immune function more than high-fat dairy in a diet-induced swine model of insulin resistance.European journal of nutrition · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity has emerged as a leading global health concern. It is characterized by chronic low-grade inflammation, which impairs insulin signaling, lipid metabolism and immune function. Recent findings from animal and clinical studies have begun to elucidate the underlying mechanisms of immune dysfunction seen in the context of obesity. Here, we provide a brief review on the current understanding of the interplay between obesity, dyslipidemia and immunity. We also emphasize the advantages and shortcomings of numerous applicable research models including rodents and large animal swine that aim at unraveling the molecular basis of disease and clinical manifestations. Although there is no perfect model to answer all questions at once, they are often used to complement each other. Finally, we highlight some emerging nutritional strategies to improve immune function in the context of obesity with a particular focus on choline and foods that contains high amounts of choline.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.