ReviewAnnual review of neuroscience2022
Breathing Rhythm and Pattern and Their Influence on Emotion.
Review in Annual review of neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07594873 (The Acute Effects of Controlled Breathing Exercises and Music Therapy on the Autonomic Nervous System in Anxious Individuals), which is not on this map. Cited by 88 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Acute Effects of Controlled Breathing Exercises and Music Therapy on the Autonomic Nervous System in Anxious Individuals: A Randomized Controlled Study
Who cites it
88 citing papers in PubMed, 1 synthesis or guideline pooled it, 138 citations in OpenAlex.
- Inconclusive evidence that breathing shapes pupil dynamics in humans: a systematic review.Pflugers Archiv : European journal of physiology · 2023Pooled it
- Yoga intervention on the fatigue-pain-sleep disturbance symptom cluster for breast cancer patients receiving adjuvant chemotherapy: a pilot randomized controlled trial.BMC complementary medicine and therapies · 2026Trial
- Find your rhythm and regulate: Breath-synced vibration feedback during breath-focused mindfulness reduces respiration variability in trauma-exposed adults.Journal of anxiety disorders · 2025Trial
- Impact of combined high-intensity bodyweight interval training and breathing exercise on cardiometabolic health in normal-weight middle-aged adults with hypertension.BMC public health · 2025Trial
- Effect of coherent breathing on mental health and wellbeing: a randomised placebo-controlled trial.Scientific reports · 2023Trial
- Slow breathing for reducing stress: The effect of extending exhale.Complementary therapies in medicine · 2023Trial
- Multimodal physiological correlates of surgeon stress in live robot-assisted surgery.Surgical endoscopy · 2026Observational
- Broca's area, responsible for speech production, is regulated by lung function.Neural regeneration research · 2026Article
- μ-Opioid receptor signalling enhances Kir3 currents in glutamatergic preBötzinger complex neurons in mice.The Journal of physiology · 2026Article
- Cardiac Autonomic Dynamics Differentially Shape Cognitive and Affective Theory of Mind: Evidence From Respiratory Manipulation.Psychophysiology · 2026Article
- A nose-to-brain circuit underlies anxiety regulation by nasal afferent frequency in mice.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The lung-brain axis in neurodegeneration: inflammatory, immune, and vascular mechanisms with therapeutic implications.Inflammopharmacology · 2026Review
- Brainstem Circuits for Rhythm Generation and Coordination of Orofacial Movements.Annual review of neuroscience · 2026Review
- TMD and Bruxism as Expressions of Central Regulatory State: The Functional Occlusion Regulated Model (FORM).Journal of clinical medicine · 2026Review
- Human forebrain neural synchronization and entrainment to breathing during wakefulness, sleep, and external mechanical ventilation.Nature communications · 2026Article
- Respiratory pauses highlight sleep architecture in mice.Nature communications · 2026Article
- A reversible rat model of hyposmia affects respiration-linked brain oscillations and behavior.iScience · 2026Article
- Respiratory Variability in Disorders of Consciousness: Relationship and Clinical Applications.CNS neuroscience & therapeutics · 2026Article
- Review
- Respiratory-Limbic Coupling via a Thalamic Circuit Alleviates Anxiety.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Breathing is a vital rhythmic motor behavior with a surprisingly broad influence on the brain and body. The apparent simplicity of breathing belies a complex neural control system, the breathing central pattern generator (bCPG), that exhibits diverse operational modes to regulate gas exchange and coordinate breathing with an array of behaviors. In this review, we focus on selected advances in our understanding of the bCPG. At the core of the bCPG is the preBötzinger complex (preBötC), which drives inspiratory rhythm via an unexpectedly sophisticated emergent mechanism. Synchronization dynamics underlying preBötC rhythmogenesis imbue the system with robustness and lability. These dynamics are modulated by inputs from throughout the brain and generate rhythmic, patterned activity that is widely distributed. The connectivity and an emerging literature support a link between breathing, emotion, and cognition that is becoming experimentally tractable. These advances bring great potential for elucidating function and dysfunction in breathing and other mammalian neural circuits.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.