ArticleNature communications2022
Ancient genomes from the Himalayas illuminate the genetic history of Tibetans and their Tibeto-Burman speaking neighbors.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- A highly prevalent lupus risk haplotype increases IRF7-dependent induction of IFN-α, enhancing antiviral defense and exacerbating autoimmunity.American journal of human genetics · 2026Article
- Paleogenomics retraces the ancient population history of Southwestern East Asia for the past 12 000 years.National science review · 2026Article
- On the Edge of Empire: Paleogenomic Insights into Roman Dacia.bioRxiv : the preprint server for biology · 2026Article
- Genetic structure and admixture of the Yi and Qiang in southwestern China.Journal of Zhejiang University. Science. B · 2026Article
- Ancient genomes reveal the genetic history of domestic goats on the Qinghai-Xizang Plateau approximately 3 600 years ago.Zoological research · 2026Article
- Ancient human genomes from Ladakh reveal Tibetan, South Asian, and Central Asian admixture over the last three millennia.bioRxiv : the preprint server for biology · 2026Article
- Ancient genomes give insight into 160,000 years of East Asian population dynamics and biological adaptation.Genome biology · 2025Review
- Ancient genomes reveal basal Asian ancestries and dynamic population interactions over time on the southern Tibetan Plateau.iScience · 2025Article
- Dynamic human admixture histories over the past ~1300 years at the northern Himalayan frontier.Science advances · 2025Article
- Human Population Genetic History and Evolutionary Dynamics on the Eastern Tibetan Plateau.Molecular biology and evolution · 2025Article
- Ancient Genomics Reveals the Origin, Dispersal, and Human Management of East Asian Domestic Pigs.Molecular biology and evolution · 2025Article
- Genomic formation of lower Yellow River populations in the Han dynasty.BMC biology · 2025Article
- Population Structure and Resource Dynamics of Three Schizothoracinae Species in the Duoxiong Zangbo River Tributary of the Yarlung Zangbo River, Tibet: Threat Assessment and Conservation Insights.Animals : an open access journal from MDPI · 2025Article
- Ancient genomes in Southwest China revealed genetic interactions among diverse populations in the historical period.BMC biology · 2025Article
- Article
- Population Structure, Growth Characteristics, Resource Dynamics, and Management Strategies ofBiology · 2025Article
- Genetic mixed diversity landscape in the paternal lineages of 11 populations inhabiting Southwest China according to the analysis of 25 Y-STRs.BMC ecology and evolution · 2025Article
- Urbanization and genetic homogenization in the medieval Low Countries revealed through a ten-century paleogenomic study of the city of Sint-Truiden.Genome biology · 2025Article
- Exploring Facial Index as an Indicator of Ethnic Lineage in Upper Himalayan Indigenous Tribal Populations.Cureus · 2025Article
- Population genomics advances in frontier ethnic minorities in China.Science China. Life sciences · 2025Review
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13 authors.
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Abstract
Present-day Tibetans have adapted both genetically and culturally to the high altitude environment of the Tibetan Plateau, but fundamental questions about their origins remain unanswered. Recent archaeological and genetic research suggests the presence of an early population on the Plateau within the past 40 thousand years, followed by the arrival of subsequent groups within the past 10 thousand years. Here, we obtain new genome-wide data for 33 ancient individuals from high elevation sites on the southern fringe of the Tibetan Plateau in Nepal, who we show are most closely related to present-day Tibetans. They derive most of their ancestry from groups related to Late Neolithic populations at the northeastern edge of the Tibetan Plateau but also harbor a minor genetic component from a distinct and deep Paleolithic Eurasian ancestry. In contrast to their Tibetan neighbors, present-day non-Tibetan Tibeto-Burman speakers living at mid-elevations along the southern and eastern margins of the Plateau form a genetic cline that reflects a distinct genetic history. Finally, a comparison between ancient and present-day highlanders confirms ongoing positive selection of high altitude adaptive alleles.
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