ArticleScientific reports2022
Evaluation of choroidal melanin-containing tissue in healthy Japanese subjects by polarization-sensitive optical coherence tomography.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 11 citations in OpenAlex.
- A hypothesis for the characteristic parafoveal toxicity observed in hydroxychloroquine retinopathy.Eye (London, England) · 2026Article
- Pigment-Resistant, Portable Corneal Fluorescence Device for Non-Invasive AGEs Monitoring in Diabetes.Biosensors · 2026Article
- Characterization of the depolarization contrast line in the outer retina using polarization-sensitive optical coherence tomography.Scientific reports · 2025Article
- Relationship Between Intraocular Pressure-Lowering Effects and Alterations in Anterior Segment Scleral Birefringence Following Micropulse Cyclophotocoagulation.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Article
- Single-Shot Ultra-Widefield Polarization-Diversity Optical Coherence Tomography for Assessing Retinal and Choroidal Pathologies.Journal of clinical medicine · 2024Article
- Spatial Distribution of Hyperreflective Choroidal Foci in the Macula of Normal Eyes.Translational vision science & technology · 2024Article
- Polarization-artifact reduction and accuracy improvement of Jones-matrix polarization-sensitive optical coherence tomography by multi-focus-averaging based multiple scattering reduction.Biomedical optics express · 2024Article
- Polarization-Diversity Optical Coherence Tomography Assessment of Choroidal Nevi.Investigative ophthalmology & visual science · 2023Article
- Quantification of choroidal hyperreflective layer: A swept-source optical coherence tomography study.PloS one · 2023Article
- Clinical and Multimodal Imaging Features of Choroidal Nevi in the Korean Population.Journal of clinical medicine · 2022Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, the choroidal melanin content in healthy eyes was evaluated with polarization-sensitive optical coherence tomography (PS-OCT). We evaluated 105 healthy eyes of 105 Japanese subjects. The mean thickness of melanin-containing tissue in the choroid (thickness of MeCh) and the choroidal melanin occupancy rate within a 5-mm circular region from the foveal center were calculated using the degree of polarization uniformity obtained by PS-OCT and compared with the choroidal thickness, patient age, and axial length. To evaluate regional variations, the 5-mm circular region was divided into a center area and an outer ring area, and the outer ring area was further divided into four areas (nasal, temporal, superior, and inferior). The mean thickness of MeCh showed a significant positive correlation with the choroidal thickness. The mean choroidal melanin occupancy rate showed a significant positive correlation with age. The mean choroidal melanin occupancy rate of the center area was significantly larger than that of the outer ring area. The mean thickness of MeCh and choroidal melanin occupancy rate of the nasal area were significantly lower than those of other areas. The distribution of melanin-containing tissue in the choroid varies significantly with age and location.
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