ArticleScientific reports2022
Higher heart rate variability as a predictor of atrial fibrillation in patients with hypertension.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07591935 (Artificial Intelligence and Mindfulness Meditation), which is not on this map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Artificial Intelligence and Mindfulness Meditation: Innovative Methods to Reduce Stress Amongst Medical School Students
Who cites it
25 citing papers in PubMed.
- Autonomic Nervous Dysfunction and Ultra-Short-Term Heart Rate Variability in Atrial Fibrillation: Recent Advances in Early Detection.Journal of cardiovascular development and disease · 2026Review
- Atrial cardiomyopathy as a multidomain disease: longitudinal evidence for autonomic remodelling.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
- From Beat to Risk: How Heart Rate Variability Predicts Arrhythmias in Type 2 Diabetes.Life (Basel, Switzerland) · 2026Review
- Heart rate variability in patients with atrial fibrillation of sinus rhythm or atrial fibrillation: chaos or merit?Annals of medicine · 2025Review
- Evaluation of Changes in Heart Rate Variability Associated with Puppy Growth Using Phase-Rectified Signal Averaging (PRSA) and Non-Gaussianity Index.Animals : an open access journal from MDPI · 2025Article
- Article
- Fully automated template matching method for ECG-free heartbeat detection in cardiomechanical signals of healthy and pathological subjects.Physical and engineering sciences in medicine · 2025Article
- Assessing heart rate fragmentation to predict atrial fibrillation in the general population aged 65: the PROOF-AF study.European heart journal open · 2025Article
- Integrated Diagnostics for Atrial Fibrillation Recurrence: Exploratory Results from the PLACEBO Trial.Diagnostics (Basel, Switzerland) · 2025Article
- Chronic rose oxide and exercise synergistically modulate cardiovascular and autonomic functions in hypertensive rats.Pflugers Archiv : European journal of physiology · 2025Article
- Prediction of the impact of anxiety on atrial fibrillation recurrence after radiofrequency catheter ablation based on heart rate variability.Frontiers in surgery · 2025Article
- Value of routine heart rate variability parameters for atrial fibrillation detection in ischaemic stroke and high-risk TIA patients.Frontiers in stroke · 2025Article
- Autonomic Nervous System Activity before Atrial Fibrillation Onset as Assessed by Heart Rate Variability.Reviews in cardiovascular medicine · 2025Article
- Heart Rate Variability in Relation to Cardiovascular Autonomic Neuropathy Among Patients at an Urban Hospital in Kazakhstan.International journal of environmental research and public health · 2024Article
- Remote monitoring of atrial fibrillation recurrence using mHealth technology (REMOTE-AF).European heart journal. Digital health · 2024Article
- Robust QRS detection based on simulated degenerate optical parametric oscillator-assisted neural network.Heliyon · 2024Article
- Very-early detection of atrial fibrillation after ablation evaluated by a wearable ECG-patch predicts late blanking period recurrence: Preliminary data from a prospective registry.International journal of cardiology. Heart & vasculature · 2024Article
- Review
- Heart Rate Variability Measurement through a Smart Wearable Device: Another Breakthrough for Personal Health Monitoring?International journal of environmental research and public health · 2023Review
- Evidence of sex differences in cancer-related cardiac complications in mouse models of pancreatic and liver cancer.Physiological reports · 2023Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The autonomic nervous system (ANS) plays an important role in the initiation and maintenance of atrial fibrillation (AF). However, the meaning of higher heart rate variability (HRV) in predicting AF remains unclear. Among 2100 patients in the Holter registry, a total of 782 hypertensive patients were included in this study. Baseline HRV was measured by time domain and frequency domain methods using 24-h Holter monitoring. The primary outcome was the development of AF. During an average follow-up of 1.1 years, 44 patients developed AF. Higher HRV parameters including high-frequency (P < 0.001), the square root of the mean squared differences of successive NN intervals (P < 0.001), and the percentage of NN intervals that are more than 50 ms different from the previous interval (P < 0.001) were associated with the occurrence of AF in univariate analysis. Premature atrial contractions burden, lower baseline heart rate, age, hemodialysis, coronary artery disease, and chronic heart failure were also associated with AF. In Cox regression analysis, higher HRV (representing excessive autonomic fluctuation) was an independent risk factor for AF. Excessive autonomic fluctuation represented by higher HRV in patients with hypertension was associated with an increased risk of AF.
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