Evidence map›Paper›PMID 35263469›Full record

ArticleExperimental dermatology2022

Hidradenitis suppurativa: Morphologic and vascular study of nodular inflammatory lesions by means of optical coherence tomography.

Marco Manfredini, Camilla Chello, Silvana Ciardo, Stefania Guida, Johanna Chester, Claudia Lasagni, Laura Bigi, Francesca Farnetani, Vincenzo Bettoli, Giovanni Pellacani

Open access · hybridAbstract read
In one paragraph

Article in Experimental dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Dermoscopy-guided high-frequency ultrasound: Principles and applications in dermatology.JID innovations : skin science from molecules to population health · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Marco ManfrediniDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0003-3601-655X
Camilla ChelloDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0002-3142-1831
Silvana CiardoDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0002-2381-2189
Stefania GuidaDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0002-8221-6694
Johanna ChesterDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0003-2866-0783
Claudia LasagniDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.
Laura BigiDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.
Francesca FarnetaniDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0001-7088-9077
Vincenzo BettoliDepartment of Dermatology, University of Ferrara, Ferrara, Italy.
Giovanni PellacaniDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0002-7222-2951
University of Modena and Reggio Emilia · ITUniversity of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hidradenitis suppurativa (HS) is an inflammatory disease characterized by a recurrent-remission trend and clinical lesions that range from asymptomatic to inflamed, deep-seated nodules with scarring and suppuration. The aim of our study was to identify morphologic and vascular features of HS nodules by means of dynamic optical coherence tomography (D-OCT) and to define if they are correlated to patient endotype and risk of disease progression. A set of standardized clinical pictures and D-OCT images were acquired from 57 inflammatory nodules of 40 patients affected by HS. A set of 20 clinical and D-OCT images were acquired from 20 healthy volunteers as a control group. The comparison of D-OCT features among HS and control group was analysed. The correlation between HS patient endotype and D-OCT features of the lesions was calculated. D-OCT enabled to identify vascular and morphological aspects characterizing HS nodular inflammatory lesions. In addition, several D-OCT features were significantly different among distinct disease endotypes. The characterization of HS nodular inflammatory lesions through D-OCT, corresponding to blood vessel dilation and inflammatory associated hyper-vascularization, may have important clinical consequences in the assessment of HS risk of progression, therapeutic decisions and treatment efficacy monitoring.

Indexed as

Hidradenitis SuppurativaHumansNeovascularization, PathologicTomography, Optical CoherenceTreatment OutcomeendotypesHidradenitis suppurativaoptical coherence tomographytherapyvascularization

Identifiers

PMID35263469
PMCPMC10286647
OpenAlexW4221014604

What Socratic holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.