Evidence map›Paper›PMID 35264702›Full record

ArticleScientific reports2022

Systolic and diastolic function during cycling at the respiratory threshold between elderly and young healthy individuals.

Sara Magnani, Gabriele Mulliri, Silvana Roberto, Giovanna Ghiani, Fabio Sechi, Silvia Stagi, Elisabetta Marini, Pier Paolo Bassareo, Marty D Spranger, Antonio Crisafulli

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Sara MagnaniDepartment of Medical Sciences and Public Health, SportsPhysiologyLaboratory, University of Cagliari, Via Porcell 4, 09124, Cagliari, Italy.
Gabriele MulliriDepartment of Medical Sciences and Public Health, SportsPhysiologyLaboratory, University of Cagliari, Via Porcell 4, 09124, Cagliari, Italy.
Silvana RobertoDepartment of Medical Sciences and Public Health, SportsPhysiologyLaboratory, University of Cagliari, Via Porcell 4, 09124, Cagliari, Italy.
Giovanna GhianiDepartment of Medical Sciences and Public Health, SportsPhysiologyLaboratory, University of Cagliari, Via Porcell 4, 09124, Cagliari, Italy.
Fabio SechiDepartment of Medical Sciences and Public Health, SportsPhysiologyLaboratory, University of Cagliari, Via Porcell 4, 09124, Cagliari, Italy.
Silvia StagiDepartment of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.
Elisabetta MariniDepartment of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.
Pier Paolo BassareoSchool of Medicine, Mater Misericordiae University Hospital, University College of Dublin, Dublin, Ireland.
Marty D SprangerDepartment of Physiology, Michigan State University, East Lansing, USA.
Antonio CrisafulliDepartment of Medical Sciences and Public Health, SportsPhysiologyLaboratory, University of Cagliari, Via Porcell 4, 09124, Cagliari, Italy. antonio.crisafulli67@gmail.com.
University of Cagliari · ITMater Misericordiae University Hospital · IEMichigan State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hemodynamic consequences of aging have been extensively investigated during maximal incremental exercise. However, less is known about the effects of aging on hemodynamics during submaximal steady-state exercise. The aim of the present investigation was to compare the hemodynamics of healthy elderly and young subjects during an exercise bout conducted at the gas threshold (GET) intensity. Two groups of healthy, physically active subjects were studied: the elderly group-EG (n = 11; > 60 years old) and the young group-YG (n = 13; < 35 years old). Both groups performed a 5-min rectangular exercise test at the GET intensity. Hemodynamics were measured using echocardiography. The main finding was that stroke volume responses were higher in the YG than the EG (72.5 ± 16.7 vs. 52.4 ± 8.4 ml, respectively). The increased stroke volume capacity in the YG was the consequence of a greater capacity to increase cardiac preload and contractility and, to a lesser extent, to reduce systemic vascular resistance. Importantly, the atrial contribution to ventricular diastolic filling was substantially higher in the YG when compared to the EG.

Indexed as

Systolic MurmursAdultAgedCardiac OutputDiastoleExerciseHemodynamicsHumansMiddle AgedStroke Volume

Identifiers

PMID35264702
PMCPMC8907329
OpenAlexW4220875059

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.