Evidence map›Paper›PMID 35265264›Full record

ArticleOxidative medicine and cellular longevity2022

Naringin protects human nucleus pulposus cells against TNF-

Renchang Chen, Shang Gao, Huapeng Guan, Xin Zhang, Yuliang Gao, Youxiang Su, Yun Song, Yuehua Jiang, Nianhu Li

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  13. Sirtuins as Players in the Signal Transduction ofInternational journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Renchang ChenShandong University of Traditional Chinese Medicine, Jinan 250355, China.
Shang GaoShandong University of Traditional Chinese Medicine, Jinan 250355, China.
Huapeng GuanSpinal Department of Orthopedics, The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250011, China.
Xin ZhangShandong University of Traditional Chinese Medicine, Jinan 250355, China.
Yuliang GaoShandong University of Traditional Chinese Medicine, Jinan 250355, China.
Youxiang SuShandong University of Traditional Chinese Medicine, Jinan 250355, China.
Yun SongShandong University of Traditional Chinese Medicine, Jinan 250355, China.
Yuehua JiangCentral Laboratory of Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250014, China.ORCID https://orcid.org/0000-0003-0156-0715
Nianhu LiSpinal Department of Orthopedics, The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250011, China.ORCID https://orcid.org/0000-0002-9260-8261
Shandong University of Traditional Chinese Medicine · CNAffiliated Hospital of Shandong University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activation of the proinflammatory-associated cytokine, tumor necrosis factor

Indexed as

AMP-Activated Protein KinasesAutophagyFlavanonesHomeostasisHumansInflammationNucleus PulposusOxidative StressSirtuin 1TransfectionTumor Necrosis Factor-alphaAMP-Activated Protein KinasesFlavanonesnaringinSIRT1 protein, humanSirtuin 1Tumor Necrosis Factor-alpha

Identifiers

PMID35265264
PMCPMC8898769
OpenAlexW4214595133

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.