Evidence map›Paper›PMID 35267952›Full record

ArticleNutrients2022

High Protein Diet Feeding Aggravates Hyperaminoacidemia in Mice Deficient in Proglucagon-Derived Peptides.

Shinji Ueno, Yusuke Seino, Shihomi Hidaka, Ryuya Maekawa, Yuko Takano, Michiyo Yamamoto, Mika Hori, Kana Yokota, Atsushi Masuda, Tatsuhito Himeno and 11 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
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  9. Hepatic FGF21: Its Emerging Role in Inter-Organ Crosstalk and Cancers.International journal of biological sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 6 institutions in 1 country.

Shinji UenoDepartments of Endocrinology, Diabetes and Metabolism, Fujita Health University Graduate School of Medicine, Toyoake 470-1192, Japan.
Yusuke SeinoDepartments of Endocrinology, Diabetes and Metabolism, Fujita Health University Graduate School of Medicine, Toyoake 470-1192, Japan.ORCID 0000-0002-9099-3493
Shihomi HidakaDepartments of Endocrinology, Diabetes and Metabolism, Fujita Health University Graduate School of Medicine, Toyoake 470-1192, Japan.
Ryuya MaekawaDepartment of Endocrinology, Hekinan City Hospital, Hekinan 447-8502, Japan.
Yuko TakanoDepartment of Clinical Oncology and Chemotherapy, Nagoya University Hospital, Nagoya 466-8550, Japan.
Michiyo YamamotoDepartment of Endocrinology, Research Institute of Environmental Medicine, Nagoya University, Nagoya 464-8601, Japan.
Mika HoriDepartment of Endocrinology, Research Institute of Environmental Medicine, Nagoya University, Nagoya 464-8601, Japan.
Kana YokotaDepartments of Endocrinology, Diabetes and Metabolism, Fujita Health University Graduate School of Medicine, Toyoake 470-1192, Japan.
Atsushi MasudaDepartments of Endocrinology, Diabetes and Metabolism, Fujita Health University Graduate School of Medicine, Toyoake 470-1192, Japan.
Tatsuhito HimenoDivision of Diabetes, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Shin TsunekawaDivision of Diabetes, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.ORCID 0000-0002-9890-5777
Hideki KamiyaDivision of Diabetes, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Jiro NakamuraDivision of Diabetes, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Hitoshi KuwataThe Division of Diabetes, Clinical Nutrition and Endocrinology, Kansai Electric Power Hospital, Osaka 553-0003, Japan.
Haruki FujisawaDepartments of Endocrinology, Diabetes and Metabolism, Fujita Health University Graduate School of Medicine, Toyoake 470-1192, Japan.
Megumi ShibataDepartments of Endocrinology, Diabetes and Metabolism, Fujita Health University Graduate School of Medicine, Toyoake 470-1192, Japan.
Takeshi TakayanagiDepartments of Endocrinology, Diabetes and Metabolism, Fujita Health University Graduate School of Medicine, Toyoake 470-1192, Japan.
Yoshihisa SugimuraDepartments of Endocrinology, Diabetes and Metabolism, Fujita Health University Graduate School of Medicine, Toyoake 470-1192, Japan.
Daisuke YabeYutaka Seino Distinguished Center for Diabetes Research, Kansai Electric Power Medical Research Institute, Kobe 650-0047, Japan.
Yoshitaka HayashiDepartment of Endocrinology, Research Institute of Environmental Medicine, Nagoya University, Nagoya 464-8601, Japan.ORCID 0000-0002-7557-4303
Atsushi SuzukiDepartments of Endocrinology, Diabetes and Metabolism, Fujita Health University Graduate School of Medicine, Toyoake 470-1192, Japan.ORCID 0000-0003-0807-199X
Fujita Health University · JPAichi Medical University · JPNagoya University · JPKansai Electric Power (Japan) · JPHekinan Technical High School · JPNagoya University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Protein stimulates the secretion of glucagon (GCG), which can affect glucose metabolism. This study aimed to analyze the metabolic effect of a high-protein diet (HPD) in the presence or absence of proglucagon-derived peptides, including GCG and GLP-1. (2) Methods: The response to HPD feeding for 7 days was analyzed in mice deficient in proglucagon-derived peptides (GCGKO). (3) Results: In both control and GCGKO mice, food intake and body weight decreased with HPD and intestinal expression of

Indexed as

Diet, High-ProteinGlucagonAnimalsGlucagon-Like Peptide 1MicePeptidesProglucagonGlucagonGlucagon-Like Peptide 1PeptidesProglucagonfood intakeglucagonhyperaminoacidemiahypoglycemiaprotein diet

Identifiers

PMID35267952
PMCPMC8912298
OpenAlexW4214725791

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.