Evidence map›Paper›PMID 35268098›Full record

Trial reportNutrients2022

A Decentralized Study Setup Enables to Quantify the Effect of Polymerization and Linkage of α-Glucans on Post-Prandial Glucose Response.

Frederik Delodder, Andreas Rytz, Fabien Foltzer, Lisa Lamothe, Carmine d'Urzo, Ludivine Feraille-Naze, Julia Mauger, Justine Morlet, Nathalie Piccardi, Lionel Philippe and 3 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 3 countries.

Frederik DelodderNestlé Research Center, 1000 Lausanne, Switzerland.
Andreas RytzNestlé Research Center, 1000 Lausanne, Switzerland.ORCID 0000-0001-5992-9154
Fabien FoltzerNestlé Research Center, 1000 Lausanne, Switzerland.
Lisa LamotheNestlé Research Center, 1000 Lausanne, Switzerland.ORCID 0000-0002-5270-1875
Carmine d'UrzoNestlé Health Science, 1000 Lausanne, Switzerland.
Ludivine Feraille-NazeNestlé Research Center, 1000 Lausanne, Switzerland.
Julia MaugerNestlé Research Center, 1000 Lausanne, Switzerland.
Justine MorletNestlé Research Center, 1000 Lausanne, Switzerland.
Nathalie PiccardiNestlé Research Center, 1000 Lausanne, Switzerland.
Lionel PhilippeNestlé Research Center, 1000 Lausanne, Switzerland.
François CaijoNestlé Research Center, 1000 Lausanne, Switzerland.
Jeroen SchmittNestlé Research Center, 1000 Lausanne, Switzerland.
Sara Colombo MottazNestlé Research Center, 1000 Lausanne, Switzerland.
Nestlé (Switzerland) · CHAgency for Science, Technology and Research · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complexity of the carbohydrate structure is associated with post-prandial glucose response and diverse health benefits. The aim of this study was to determine whether, thanks to the usage of minimally invasive glucose monitors, it was possible to evaluate, in a decentralized study setup, the post-prandial glycemic response (PPGR) of α-glucans differing systematically in their degree of polymerization (DP 3 vs. DP 60) and in their linkage structure (dextrin vs. dextran). Ten healthy subjects completed a double-blind, randomized, decentralized crossover trial, testing at home, in real life conditions, four self-prepared test beverages consisting of 25 g α-glucan dissolved in 300 mL water. The incremental area under the curve of the 120 min PPGR (2h-iAUC) was the highest for Dextrin DP 3 (163 ± 27 mmol/L*min), followed by Dextrin DP 60 (-25%,

Indexed as

GlucansGlucoseCross-Over StudiesHumansPolymerizationPostprandial PeriodGlucansGlucosedecentralized study designpolymerizationpost-prandial glucose response (PPGR)α-glucans

Identifiers

PMID35268098
PMCPMC8912759
OpenAlexW4221105841

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.