Evidence map›Paper›PMID 35268705›Full record

ArticleMolecules (Basel, Switzerland)2022

Comparative Proteomic Analysis of Drug Trichosanthin Addition to BeWo Cell Line.

Yajun Hu, Jun Yao, Zening Wang, Hui Liang, Cunyu Li, Xinwen Zhou, Fengying Yang, Yang Zhang, Hong Jin

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Survey of Acetylation for Thermoanaerobacter tengcongensis.Applied biochemistry and biotechnology · 2023
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yajun HuShanghai Stomatological Hospital & School of Stomatology, Fudan University, 356 Beijing East Road, Shanghai 200001, China.
Jun YaoDepartment of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China.
Zening WangInstitutes of Biomedical Sciences, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China.
Hui LiangCollege of Pharmacy, Guangxi Medical University, 22 Shuangyong Road, Nanning 530031, China.
Cunyu LiInstitutes of Biomedical Sciences, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China.
Xinwen ZhouInstitutes of Biomedical Sciences, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China.
Fengying YangInstitutes of Biomedical Sciences, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China.
Yang ZhangShanghai Stomatological Hospital & School of Stomatology, Fudan University, 356 Beijing East Road, Shanghai 200001, China.ORCID 0000-0002-8856-266X
Hong JinShanghai Stomatological Hospital & School of Stomatology, Fudan University, 356 Beijing East Road, Shanghai 200001, China.
Fudan University · CNGuangxi Medical University · CN

Funding

National Key R&D Program of China 2021YFF0703702
6 · The paper itself

Abstract

Trichosanthin (TCS) is a traditional Chinese herbal medicine used to treat some gynecological diseases. Its effective component has diverse biological functions, including antineoplastic activity. The human trophoblast cell line BeWo was chosen as an experimental model for in vitro testing of a drug screen for anticancer properties of TCS. The MTT method was used in this study to get a primary screen result. The result showed that 100 mM had the best IC

Indexed as

Antineoplastic AgentsTrichosanthinCell LineHumansProteinsProteomicsAntineoplastic AgentsProteinsTrichosanthinBeWo cell lineMALDI-TOF/TOF MSMTTproteomicTCS

Identifiers

PMID35268705
PMCPMC8911981
OpenAlexW4214576221

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.