ReviewNanomaterials (Basel, Switzerland)2022
Magnetic Nanoparticles in Bone Tissue Engineering.
Review in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed.
- Magnetic Cellulose Nanocrystal Composites: Synthesis, Properties, Applications, and Opportunities.Nanomaterials (Basel, Switzerland) · 2026Review
- Nanoparticle Strategies for Bone Metastasis Immunotherapy: Targeting, Immune Reprogramming and Combination Therapy.Pharmaceutics · 2026Review
- Cellular Crosstalk Within Magnetically Functionalised Hydrogel-Composite Scaffolds for Enhanced Vascularisation and Bone Repair.Gels (Basel, Switzerland) · 2026Article
- Therapeutic Biomaterials for Chronic Osteomyelitis: Time-Space-Control Strategies for Infection Control and Bone Repair-A Narrative Review.Journal of functional biomaterials · 2026Review
- Biopolymer Casein-Pullulan Coating of FePolymers · 2026Article
- Magnetic nanoparticle formulations to activate TREK and Piezo mechanosensitive ion channels (MICA) for enhanced osteogenesis.Regenerative biomaterials · 2026Article
- Calcium-Enriched Magnetic Core-Shell Mesoporous Nanoparticles for Potential Application in Bone Regeneration.Nanomaterials (Basel, Switzerland) · 2025Article
- Multiscale Construction, Evaluation, and Application of Organoids.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Magnetic Nanoparticles: Synthesis and Applications in Life Sciences.ChemistryOpen · 2025Review
- Magnetized Cell-Scaffold Constructs for Bone Tissue Engineering: Advances in Fabrication and Magnetic Stimulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Modular Flow Synthesis of Citric Acid-Coated Superparamagnetic Iron Oxide Nanoparticles: Preliminary Results.Micromachines · 2025Article
- Novel Nanomaterials for Developing Bone Scaffolds and Tissue Regeneration.Nanomaterials (Basel, Switzerland) · 2025Review
- Novel Magnetically Charged Grafts for Vascular Repair: Process Optimization, Mechanical Characterization and In Vitro Validation.Polymers · 2025Article
- Promising biomedical applications using superparamagnetic nanoparticles.European journal of medical research · 2025Review
- Multiscale metal-based nanocomposites for bone and joint disease therapies.Materials today. Bio · 2025Review
- Evolution in Bone Tissue Regeneration: From Grafts to Innovative Biomaterials.International journal of molecular sciences · 2025Review
- Innovative Approaches in Bone Tissue Engineering: Strategies for Cancer Treatment and Recovery.International journal of molecular sciences · 2025Review
- Advances in 3D printing combined with tissue engineering for nerve regeneration and repair.Journal of nanobiotechnology · 2025Review
- Imparting of Nearly Superparamagnetic Properties to Cryogel Scaffolds With Mesoporous MNPs for Magneto-Sensitive Tissue Engineering Strategies.Biopolymers · 2024Article
- Enhancing bone regeneration: Unleashing the potential of magnetic nanoparticles in a microtissue model.Journal of cellular and molecular medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Large bone defects with limited intrinsic regenerative potential represent a major surgical challenge and are associated with a high socio-economic burden and severe reduction in the quality of life. Tissue engineering approaches offer the possibility to induce new functional bone regeneration, with the biomimetic scaffold serving as a bridge to create a microenvironment that enables a regenerative niche at the site of damage. Magnetic nanoparticles have emerged as a potential tool in bone tissue engineering that leverages the inherent magnetism of magnetic nano particles in cellular microenvironments providing direction in enhancing the osteoinductive, osteoconductive and angiogenic properties in the design of scaffolds. There are conflicting opinions and reports on the role of MNPs on these scaffolds, such as the true role of magnetism, the application of external magnetic fields in combination with MNPs, remote delivery of biomechanical stimuli in-vivo and magnetically controlled cell retention or bioactive agent delivery in promoting osteogenesis and angiogenesis. In this review, we focus on the role of magnetic nanoparticles for bone-tissue-engineering applications in both disease modelling and treatment of injuries and disease. We highlight the materials-design pathway from implementation strategy through the selection of materials and fabrication methods to evaluation. We discuss the advances in this field and unmet needs, current challenges in the development of ideal materials for bone-tissue regeneration and emerging strategies in the field.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.