Evidence map›Paper›PMID 35269802›Full record

ArticleInternational journal of molecular sciences2022

A Redox-Silent Analogue of Tocotrienol May Break the Homeostasis of Proteasomes in Human Malignant Mesothelioma Cells by Inhibiting STAT3 and NRF1.

Kyota Ishii, Momoka Fusegi, Tatsuki Mori, Kosuke Teshima, Nanako Ninomiya, Kakeru Kohno, Ayami Sato, Tatsuya Ishida, Yuichi Miyakoshi, Tomohiro Yano

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kyota IshiiLaboratory of Molecular Bromacology, Graduate School of Food and Nutritional Sciences, Toyo University, Oura District, Gunma, Itakura Town 374-0193, Japan.
Momoka FusegiLaboratory of Molecular Bromacology, Graduate School of Food and Nutritional Sciences, Toyo University, Oura District, Gunma, Itakura Town 374-0193, Japan.
Tatsuki MoriDepartment of Food and Life Sciences, Faculty of Food and Nutritional Sciences, Toyo University, Oura District, Gunma, Itakura Town 374-0193, Japan.
Kosuke TeshimaDepartment of Food and Life Sciences, Faculty of Food and Nutritional Sciences, Toyo University, Oura District, Gunma, Itakura Town 374-0193, Japan.
Nanako NinomiyaDepartment of Food and Life Sciences, Faculty of Food and Nutritional Sciences, Toyo University, Oura District, Gunma, Itakura Town 374-0193, Japan.
Kakeru KohnoResearch Institute of Life Innovation, Toyo University, Oura District, Gunma, Itakura Town 374-0193, Japan.
Ayami SatoResearch Institute of Life Innovation, Toyo University, Oura District, Gunma, Itakura Town 374-0193, Japan.
Tatsuya IshidaResearch Institute of Life Innovation, Toyo University, Oura District, Gunma, Itakura Town 374-0193, Japan.
Yuichi MiyakoshiResearch Institute of Life Innovation, Toyo University, Oura District, Gunma, Itakura Town 374-0193, Japan.
Tomohiro YanoResearch Institute of Life Innovation, Toyo University, Oura District, Gunma, Itakura Town 374-0193, Japan.ORCID 0000-0002-9490-3424
Toyo University · JP

Funding

Japan Society for the Promotion of Science 18K11058
6 · The paper itself

Abstract

6-

Indexed as

MesotheliomaMesothelioma, MalignantTocotrienolsCell Line, TumorHomeostasisHumansOxidation-ReductionProteasome Endopeptidase ComplexSTAT3 Transcription FactorProteasome Endopeptidase ComplexSTAT3 protein, humanSTAT3 Transcription FactorTocotrienolscytotoxicityER stressmalignant mesothelioma cellsNRF1proteasome inhibitorredox-silent analogueSTAT3tocotrienol

Identifiers

PMID35269802
PMCPMC8910454
OpenAlexW4214724840

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.