Evidence map›Paper›PMID 35272055›Full record

ReviewJournal of pediatric and adolescent gynecology2022

The Care of Adolescents and Young Adults with Turner Syndrome: A Pediatric and Adolescent Gynecology Perspective.

Tazim Dowlut-McElroy, Roopa Kanakatti Shankar

Registry-linked trialOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of pediatric and adolescent gynecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06834594 (Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06834594 phase4recruitingnot on this mapstarted 2025, after this paper: background citation

Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome: A Non-randomized Prospective Trial (The BOOST Study)

TypeinterventionalSponsorChildren's Mercy Hospital Kansas CityRan2025 to 2028Enrolled40ConditionsTurner Syndrome, Primary Ovarian Insufficiency (Poi)ArmsMicronized progesterone 200 MG, Micronized Progesterone 100 MG
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Unlocking Novel Therapeutic Potential of Angiotensin II Receptor Blockers.International journal of molecular sciences · 2025
    Review
  4. Primary Ovarian Insufficiency, Bone Health, and Other Outcomes in Adolescents.Obstetrics and gynecology clinics of North America · 2024
    Review
  5. Primary Amenorrhea and Premature Ovarian Insufficiency.Endocrinology and metabolism clinics of North America · 2024
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Tazim Dowlut-McElroyPediatric and Adolescent Gynecology, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD, USA; Department of Surgery, Children's National Hospital, Washington, DC, USA. Electronic address: tazim.dowlut-mcelroy@nih.gov.
Roopa Kanakatti ShankarDivision of Endocrinology, Children's National Hospital, Washington, DC, USA; George Washington University School of Medicine, Washington, DC, USA.
Children's National · USEunice Kennedy Shriver National Institute of Child Health and Human Development · US

Funding

Pediatric and Adolescent Gynecology Training ProgramZIAHD008985 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI GOMEZ-LOBO, VERONICA · 2019 to 2021
$5.3M
Intramural NIH HHS ZIA HD008985
6 · The paper itself

Abstract

Turner syndrome (TS) is caused by the absence of a part or whole X chromosome in a phenotypic female and has an estimated prevalence of 25-50/100,000 live-born females. The primary gynecologic manifestation of TS is primary ovarian insufficiency (POI), and the resulting hypoestrogenism and infertility are experienced by most individuals with TS. In this review, we summarize the recommendations for the care of adolescents and young adults with TS, with a focus on primary ovarian insufficiency in TS, hormone replacement therapy, fertility preservation, and pregnancy in TS.

Indexed as

Fertility PreservationGynecologyInfertilityPrimary Ovarian InsufficiencyTurner SyndromeAdolescentChildFemaleHumansPregnancyYoung AdultDSDFertilityHormone replacement therapyPOIPregnancy complicationsPreservationPubertal inductionTurner syndrome

Identifiers

PMID35272055
PMCPMC9288983
OpenAlexW4221027687

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.