Evidence map›Paper›PMID 35273344›Full record

ArticleScientific reports2022

Short-term inhalation of isoflurane improves the outcomes of intraportal hepatocyte transplantation.

Hiroyasu Nishimaki, Yoshikatsu Saitoh, Akiko Inagaki, Yasuhiro Nakamura, Takehiro Imura, Ibrahim Fathi, Hiroki Yamana, Kazuo Ohashi, Shigehito Miyagi, Takashi Kamei and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Hiroyasu NishimakiDepartment of Surgery, Tohoku University Graduate School of Medicine, Sendai, 980-0872, Japan.
Yoshikatsu SaitohDepartment of Surgery, Tohoku University Graduate School of Medicine, Sendai, 980-0872, Japan.
Akiko InagakiDivision of Transplantation and Regenerative Medicine, Tohoku University Graduate School of Medicine, 980-0872, Sendai, Japan.
Yasuhiro NakamuraDivision of Pathology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, 983-8536, Japan.
Takehiro ImuraDivision of Transplantation and Regenerative Medicine, Tohoku University Graduate School of Medicine, 980-0872, Sendai, Japan.
Ibrahim FathiDivision of Transplantation and Regenerative Medicine, Tohoku University Graduate School of Medicine, 980-0872, Sendai, Japan.
Hiroki YamanaDepartment of Surgery, Tohoku University Graduate School of Medicine, Sendai, 980-0872, Japan.
Kazuo OhashiGraduate School and School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan.
Shigehito MiyagiDepartment of Surgery, Tohoku University Graduate School of Medicine, Sendai, 980-0872, Japan.
Takashi KameiDepartment of Surgery, Tohoku University Graduate School of Medicine, Sendai, 980-0872, Japan.
Michiaki UnnoDepartment of Surgery, Tohoku University Graduate School of Medicine, Sendai, 980-0872, Japan.
Masafumi GotoDepartment of Surgery, Tohoku University Graduate School of Medicine, Sendai, 980-0872, Japan. masafumi.goto.c6@tohoku.ac.jp.
Tohoku University · JPOsaka University · JPTohoku Medical and Pharmaceutical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical hepatocyte transplantation (HTx) is only performed without general anesthesia, while inhalation anesthetics are usually used in animal experiments. We hypothesized that isoflurane may be a possible reason for the discrepancy between the results of animal experiments and the clinical outcomes of HTx. Syngeneic rat hepatocytes (1.0 × 10

Indexed as

Anesthetics, InhalationIsofluraneLiver TransplantationAnimalsHepatocytesLiverRatsSerum AlbuminAnesthetics, InhalationIsofluraneSerum Albumin

Identifiers

PMID35273344
PMCPMC8913608
OpenAlexW4221057391

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.