ReviewFrontiers in neurology2022
Critical to Know Pcrit: A Review on Pharyngeal Critical Closing Pressure in Obstructive Sleep Apnea.
Review in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Reducing Obstructive Sleep Apnea After Hypoglossal Nerve Stimulation Through
Assessment of the Effect of Hypoglossal Nerve Stimulation Therapy on Upper Airway Collapsibility During Drug-induced Sleep Endoscopy
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Anatomical determinants of upper airway collapsibility in obstructive sleep apnea: A systematic review and meta-analysis.Sleep medicine reviews · 2023Pooled it
- Nasopharyngeal tube effects on alleviating sleep hypoxemia during the first night following velopharyngeal surgery in patients with obstructive sleep apnea syndrome.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023Trial
- Preoperative video laryngoscopic examination for difficult intubation in obese patients.Die Anaesthesiologie · 2026Article
- GLP-1 Receptor Agonists in Obstructive Sleep Apnea: A Translational Perspective on Mechanisms and Clinical Implications.International journal of molecular sciences · 2026Review
- The Pharyngeal Resistance Index-A Promising Diagnostic Tool in OSA.Journal of sleep research · 2026Article
- Translating hypoglossal nerve stimulation tongue movement into functional response during drug-induced sleep endoscopy: a proof-of-concept study.Sleep & breathing = Schlaf & Atmung · 2026Article
- The upper airway in obstructive sleep apnoea: state of the art.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Characterizing inspiratory duty cycle compensation to flow-limited breathing during drug-induced sleep endoscopy in obstructive sleep apnea.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Article
- Mechanisms and Management of Obstructive Sleep Apnea: A Translational Overview.Clinical and experimental otorhinolaryngology · 2025Review
- Ascending and Descending Pharyngeal Opening Pressures During Drug-Induced Sleep Endoscopy: Mechanistic Insights for Sleep Surgeons.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Article
- Using DISE to characterize upper airway collapse and ventilatory characteristics in modeling obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2025Article
- Tissue-specified reconstruction modeling of the head and neck structure and its application in simulating airway obstruction.Heliyon · 2025Article
- Ansa cervicalis stimulation effects on upper airway patency: a structure-based analysis.The European respiratory journal · 2025Article
- Phenotypes of Velopharyngeal Tube Law in Obstructive Sleep Apnea.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Article
- Case-control study of heart rate variability and sleep apnea in childhood sickle cell disease.Journal of sleep research · 2024Article
- Airway Collapsibility during Drug-Induced Sleep Endoscopy Relates with Clinical Features of Obstructive Sleep Apnea.The Laryngoscope · 2024Article
- Metabolic Crossroads: Unveiling the Complex Interactions between Obstructive Sleep Apnoea and Metabolic Syndrome.International journal of molecular sciences · 2024Review
- The Present and Future of the Clinical Use of Physiological Traits for the Treatment of Patients with OSA: A Narrative Review.Journal of clinical medicine · 2024Review
- Sleep parameter characteristics of patients with OSA who have retropalatal circumferential narrowing and the clinical significance of lateral pharyngeal wall collapse during sleep.Sleep & breathing = Schlaf & Atmung · 2023Article
- Buckling critical pressures in collapsible tubes relevant for biomedical flows.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is crucial to understand the underlying pathophysiology of obstructive sleep apnea (OSA). Upper airway collapsibility is an important pathophysiological factor that affects the upper airway in OSA. The aim of the current study was to review the existing body of knowledge on the pharyngeal collapsibility in OSA. After a thorough search through Medline, PubMed, Scopus, and Web of science, the relevant articles were found and used in this study. Critical closing pressure (Pcrit) is the gold standard measure for the degree of collapsibility of the pharyngeal airway. Various physiological factors and treatments affect upper airway collapsibility. Recently, it has been shown that the baseline value of Pcrit is helpful in the upfront selection of therapy options. The standard techniques to measure Pcrit are labor-intensive and time-consuming. Therefore, despite the importance of Pcrit, it is not routinely measured in clinical practice. New emerging surrogates, such as finite element (FE) modeling or the use of peak inspiratory flow measurements during a routine overnight polysomnography, may enable clinicians to have an estimate of the pharyngeal collapsibility. However, validation of these techniques is needed.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.