Evidence map›Paper›PMID 35274398›Full record

ArticleEuropean eating disorders review : the journal of the Eating Disorders Association2022

Urinary free cortisol and childhood maltreatments in eating disorder patients: New evidence for an ecophenotype subgroup.

Paolo Meneguzzo, Cecilia Mancini, Samira Terlizzi, Chiara Sales, Maria Federica Francesconi, Patrizia Todisco

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In one paragraph

Article in European eating disorders review : the journal of the Eating Disorders Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Eye movement desensitization and reprocessingResearch in psychotherapy (Milano) · 2026
    Article
  2. Review
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  4. Network dynamics of self-compassion, anxiety, and depression during eating disorder therapy.European eating disorders review : the journal of the Eating Disorders Association · 2025
    Article
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  15. Urinary free cortisol and childhood maltreatments in eating disorder patients: New evidence for an ecophenotype subgroup.European eating disorders review : the journal of the Eating Disorders Association · 2022
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paolo MeneguzzoEating Disorders Unit, Casa di Cura, "Villa Margherita", Arcugnano (VI), Vicenza, Italy.ORCID 0000-0003-3323-6071
Cecilia ManciniExperimental Medicine Department, Food Science and Human Nutrition Research Unit, Sapienza University of Rome, Rome, Italy.
Samira TerlizziEating Disorders Unit, Casa di Cura, "Villa Margherita", Arcugnano (VI), Vicenza, Italy.
Chiara SalesEating Disorders Unit, Casa di Cura, "Villa Margherita", Arcugnano (VI), Vicenza, Italy.
Maria Federica FrancesconiEating Disorders Unit, Casa di Cura, "Villa Margherita", Arcugnano (VI), Vicenza, Italy.
Patrizia TodiscoEating Disorders Unit, Casa di Cura, "Villa Margherita", Arcugnano (VI), Vicenza, Italy.ORCID 0000-0002-2212-9855

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIncreasing neurobiological evidence has suggested the presence of a specific ecophenotype in people with eating disorders (EDs) linked to early maltreatment. Urinary-free cortisol could strengthen the data and show specific relationships between maltreated subtypes and the hormonal profiles of patients with EDs. This study aims to evaluate the presence of different urinary cortisol in drug-free patients in the acute phase of the disorder and its relationship with childhood maltreatment.

methodsA sample of 78 female patients with ED is included in the study. Childhood maltreatment history and 24-h urinary free cortisol (24-h UFC) are evaluated at a specialised ED ward admission.

resultsPatients with a maltreatment history show more blunted 24-h UFC levels than peers without childhood maltreatment (p = 0.001). Regression analysis showed that child abuse is a predictor of the reduction of 24-h UFC (p < 0.001), with physical abuse (p = 0.011) and sexual abuse (p = 0.050) that could have a more specific impact than other maltreatment subtypes. DISCUSSION: Childhood maltreatment should be evaluated in ED patients due to its biological impact on the hormonal stress axis, which could impair the ability of patients to respond to standardized ED treatment.

Indexed as

Child AbuseFeeding and Eating DisordersChildFemaleHumansHydrocortisoneHydrocortisone24-h urinary free cortisolchild maltreatmentcortisoleating disorder

Identifiers

PMID35274398
PMCPMC9314975

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.