Evidence map›Paper›PMID 35274501›Full record

ArticleThe world journal of men's health2023

Myocardin Reverses Hypoxia-Inducible Factor-1α Mediated Phenotypic Modulation of Corpus Cavernosum Smooth Muscle Cells in Hypoxia Induced by Cobalt Chloride.

Xiongcai Zhou, Chao Luo, Junhong Fan, Guangqian Gao, Tao Wang, Haibo Zhang, Anyang Wei

Open access · diamondAbstract read
In one paragraph

Article in The world journal of men's health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Xiongcai Zhou *Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0001-9923-6125
Chao Luo *Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-5370-8331
Junhong FanDepartment of Urology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-6564-0987
Guangqian GaoDepartment of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0001-6166-4781
Tao WangDepartment of Andrology, The Third Affiliated Hospital of Guangdong Medical University, Foshan, Guangdong, China. job1982@126.com.ORCID https://orcid.org/0000-0002-4189-7155
Haibo ZhangDepartment of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China. hai516@163.com.ORCID https://orcid.org/0000-0002-1619-7296
Anyang WeiDepartment of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China. profwei@126.com.ORCID https://orcid.org/0000-0001-7585-8210
Nanfang Hospital · CNGuangdong Academy of Medical Sciences · CNGuangdong Medical College · CN

Funding

Basic and Applied Basic Research Foundation of Guangdong Province 2020A1515010114National Natural Science Foundation of China 82171612Scientific Research Fund of Guangdong Medical University GDMUZ201812
6 · The paper itself

Abstract

purposeWe aimed to investigate the mechanism of phenotypic transformation of corporal cavernosum smooth muscle cells (CCSMCs) under hypoxic conditions MATERIALS AND

methodsIn this study, a hypoxia model was established using cobalt chloride (CoCl

resultsCoCl

conclusionsOur findings showed that HIF-1α was involved in the effect of hypoxia induced by CoCl

Indexed as

HypoxiaMyocardinMyocytes, smooth musclePhenotype

Identifiers

PMID35274501
PMCPMC10042661
OpenAlexW4212928311

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.