Evidence map›Paper›PMID 35277372›Full record

ArticleJournal of geriatric oncology2022

Caregiver-oncologist prognostic concordance, caregiving esteem, and caregiver outcomes.

Kah Poh Loh, Erin Watson, Eva Culakova, Marie Flannery, Michael Sohn, Huiwen Xu, Sindhuja Kadambi, Allison Magnuson, Colin McHugh, Chandrika Sanapala and 6 more

Abstract read
In one paragraph

Article in Journal of geriatric oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Family caregiver roles and challenges in assisting patients with cancer treatment decision-making: Analysis of data from a national survey.Health expectations : an international journal of public participation in health care and health policy · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kah Poh LohDivision of Hematology/Oncology, Department of Medicine, James P Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: kahpoh_loh@urmc.rochester.edu.
Erin WatsonDivision of Hematology/Oncology, Department of Medicine, James P Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: erin_watson@urmc.rochester.edu.
Eva CulakovaDepartment of Surgery, Cancer Control, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: eva_culakova@urmc.rochester.edu.
Marie FlannerySchool of Nursing, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: marie_flannery@urmc.rochester.edu.
Michael SohnDepartment of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: Michael_sohn@urmc.rochester.edu.
Huiwen XuPreventive Medicine and Population Health University of Texas Medical Branch, Galveston, TX, USA. Electronic address: huiwen_xu@urmc.rochester.edu.
Sindhuja KadambiDivision of Hematology/Oncology, Department of Medicine, James P Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: sindhuja_kadambi@urmc.rochester.edu.
Allison MagnusonDivision of Hematology/Oncology, Department of Medicine, James P Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: allison_magnuson@urmc.rochester.edu.
Colin McHughDivision of Hematology/Oncology, Department of Medicine, James P Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: colin_mchugh@urmc.rochester.edu.
Chandrika SanapalaDivision of Hematology/Oncology, Department of Medicine, James P Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: chandrika_sanapala@urmc.rochester.edu.
Lee KehoeDepartment of Surgery, Cancer Control, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: lee_kehoe@urmc.rochester.edu.
Victor G VogelGeisinger Cancer Institute NCORP, Danville, PA, USA. Electronic address: vgvogel@geisinger.edu.
Brian L BurnetteCancer Research of Wisconsin and Northern Michigan (CROWN), Green Bay, WI, USA. Electronic address: brian.Burnette@gboncology.com.
Vincent VinciguerraNorthwell Health, New York, USA. Electronic address: vvincigu@northwell.edu.
Supriya G MohileDivision of Hematology/Oncology, Department of Medicine, James P Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: supriya_mohile@urmc.rochester.edu.
Paul R DubersteinDepartment of Health Behavior, Society, and Policy, Rutgers School of Public Health, Piscataway, NJ, USA. Electronic address: paul.duberstein@rutgers.edu.

Funding

URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
Geriatric Oncology Research Infrastructure to Improve Clinical CareR33AG059206 · NIA · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI WILLIAM DALE, Heidi Diana Klepin · 2020 to 2026
$5.1M
Impact of a Novel Cancer Communication Intervention on Caregiver BereavementR01CA168387 · NCI · UNIVERSITY OF ROCHESTER · PI DUBERSTEIN, PAUL R, PRIGERSON, HOLLY GWEN · 2013 to 2017
$2.6M
A Patient-Oriented Research Program in Geriatric OncologyK24AG056589 · NIA · UNIVERSITY OF ROCHESTER · PI Supriya G. Mohile · 2018 to 2026
$1.5M
Mitigating Cancer-Related Cognitive Dysfunction in Older Adults with Breast CancerK76AG064394 · NIA · UNIVERSITY OF ROCHESTER · PI MAGNUSON, ALLISON MARIAN · 2019 to 2023
$1.3M
A novel mobile health exercise intervention for older patients with myeloid neoplasmsR00CA237744 · NCI · UNIVERSITY OF ROCHESTER · PI LOH, KAH POH · 2021 to 2023
$747k
Geriatric Oncology Research Infrastructure to Improve Clinical CareR21AG059206 · NIA · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI DALE, WILLIAM, MOHILE, SUPRIYA G. · 2018 to 2019
$478k
A Novel Mobile Health Exercise Intervention for Older Patients with Myeloid NeoplasmsK99CA237744 · NCI · UNIVERSITY OF ROCHESTER · PI LOH, KAH POH · 2019 to 2020
$385k
NCI NIH HHS K99 CA237744NCI NIH HHS R00 CA237744NCI NIH HHS R01 CA168387NCI NIH HHS UG1 CA189961NIA NIH HHS K24 AG056589NIA NIH HHS K76 AG064394NIA NIH HHS R21 AG059206NIA NIH HHS R33 AG059206
6 · The paper itself

Abstract

introductionCaregiver-oncologist concordance regarding the patient's prognosis is associated with worse caregiver outcomes (e.g., depressive symptoms), but mechanisms underpinning these associations are unclear. We explored whether caregiving esteem mediates these associations.

methodsAt enrollment, caregivers and oncologists used a 5-point ordinal scale to estimate patient survival; identical responses were considered concordant. At 4-6 weeks, caregivers completed an assessment of the extent to which caregiving imparts self-esteem (Caregiver Reaction Assessment self-esteem subscale; range 0-5; higher score indicates greater esteem). They also completed Patient Health Questionnaire-2 (PHQ-2) for depressive symptoms, Distress Thermometer, and 12-Item Short Form Survey for quality of life (QoL). Mediation analysis with bootstrapping (PROCESS macro by Hayes) was used to estimate the extent to which caregiving mediated the effects of prognostic concordance on caregiver outcomes through caregiving esteem.

resultsPrognostic concordance occurred in 28% the caregiver-oncologist dyads; 85% of the discordance were due to caregivers estimating a longer patient's survival. At 4-6 weeks, mean caregiving esteem score was 4.4 (range 1.5-5.0). Lower caregiving esteem mediated the associations of concordance with higher PHQ-2 [indirect effect = 0.12; 95% Confidence Interval (CI) 0.03, 0.27], greater distress (indirect effect =0.25; 95% CI 0.08, 0.48), and poorer QoL (indirect effect = -1.50; 95% CI -3.06, -0.41). Caregiving esteem partially mediated 39%, 64%, and 48% of the associations between caregiver-oncologist concordance and PHQ-2, distress, and SF-12, respectively.

conclusionsCaregiver-oncologist concordance was associated with lower caregiving esteem. Lower caregiving esteem mediated the negative relationship between caregiver-oncologist concordance and caregiver outcomes.

Indexed as

CaregiversOncologistsHumansPrognosisQuality of LifeSurveys and QuestionnairesCaregiverDepressive symptomDistressPrognostic understandingQuality of life

Identifiers

PMID35277372
PMCPMC9283218

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.