Evidence map›Paper›PMID 35277476›Full record

ArticleNature communications2022

Secondary structure prediction for RNA sequences including N

Elzbieta Kierzek, Xiaoju Zhang, Richard M Watson, Scott D Kennedy, Marta Szabat, Ryszard Kierzek, David H Mathews

Abstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Article
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  6. Article
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  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Prediction of Circular RNA Secondary Structures and Their Targets.Advances in experimental medicine and biology · 2025
    Review
  14. StructRMDB: A database of RNA modification sites that affect RNA secondary structure.Computational and structural biotechnology journal · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elzbieta KierzekInstitute of Bioorganic Chemistry Polish Academy of Sciences, Noskowskiego 12/14, 61-704, Poznan, Poland. Elzbieta.Kierzek@ibch.poznan.pl.ORCID http://orcid.org/0000-0002-5563-003X
Xiaoju ZhangDepartment of Biochemistry and Biophysics and Center for RNA Biology, School of Medicine and Dentistry, University of Rochester, 601 Elmwood Avenue, Box 712, Rochester, NY, 14642, USA.
Richard M WatsonDepartment of Biochemistry and Biophysics and Center for RNA Biology, School of Medicine and Dentistry, University of Rochester, 601 Elmwood Avenue, Box 712, Rochester, NY, 14642, USA.
Scott D KennedyDepartment of Biochemistry and Biophysics and Center for RNA Biology, School of Medicine and Dentistry, University of Rochester, 601 Elmwood Avenue, Box 712, Rochester, NY, 14642, USA.ORCID http://orcid.org/0000-0001-9792-8726
Marta SzabatInstitute of Bioorganic Chemistry Polish Academy of Sciences, Noskowskiego 12/14, 61-704, Poznan, Poland.
Ryszard KierzekInstitute of Bioorganic Chemistry Polish Academy of Sciences, Noskowskiego 12/14, 61-704, Poznan, Poland.
David H MathewsDepartment of Biochemistry and Biophysics and Center for RNA Biology, School of Medicine and Dentistry, University of Rochester, 601 Elmwood Avenue, Box 712, Rochester, NY, 14642, USA. David_Mathews@urmc.rochester.edu.ORCID http://orcid.org/0000-0002-2907-6557

Funding

Supporting RNAstructure: Software for RNA AnalysisR01GM076485 · NIGMS · UNIVERSITY OF ROCHESTER · PI MATHEWS, DAVID H. · 2006 to 2021
$4.7M
NIGMS NIH HHS R01 GM076485
6 · The paper itself

Abstract

There is increasing interest in the roles of covalently modified nucleotides in RNA. There has been, however, an inability to account for modifications in secondary structure prediction because of a lack of software and thermodynamic parameters. We report the solution for these issues for N

Indexed as

RNASoftwareAdenosineBase SequenceHumansNucleic Acid ConformationThermodynamicsAdenosineN-methyladenosineRNA

Identifiers

PMID35277476
PMCPMC8917230

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.