Evidence map›Paper›PMID 35279134›Full record

ArticleJournal of nanobiotechnology2022

Highly sensitive near-infrared SERS nanoprobes for in vivo imaging using gold-assembled silica nanoparticles with controllable nanogaps.

Sungje Bock, Yun-Sik Choi, Minhee Kim, Yewon Yun, Xuan-Hung Pham, Jaehi Kim, Bomi Seong, Wooyeon Kim, Ahla Jo, Kyeong-Min Ham and 8 more

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Review
  3. Recent Advancements in the SERS-Based Detection ofSensors (Basel, Switzerland) · 2026
    Review
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  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
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  14. Article
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  17. Article
  18. Article
  19. Advanced Optical Materials: From Materials to Applications.International journal of molecular sciences · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Sungje Bock *Department of Bioscience and Biotechnology, Konkuk University, Seoul, 05029, South Korea.
Yun-Sik Choi *Department of Chemistry Education, Seoul National University, Seoul, 08826, South Korea.
Minhee Kim *Department of Bioscience and Biotechnology, Konkuk University, Seoul, 05029, South Korea.
Yewon YunDepartment of Bioscience and Biotechnology, Konkuk University, Seoul, 05029, South Korea.
Xuan-Hung PhamDepartment of Bioscience and Biotechnology, Konkuk University, Seoul, 05029, South Korea.
Jaehi KimDepartment of Bioscience and Biotechnology, Konkuk University, Seoul, 05029, South Korea.
Bomi SeongDepartment of Bioscience and Biotechnology, Konkuk University, Seoul, 05029, South Korea.
Wooyeon KimDepartment of Bioscience and Biotechnology, Konkuk University, Seoul, 05029, South Korea.
Ahla JoDepartment of Bioscience and Biotechnology, Konkuk University, Seoul, 05029, South Korea.
Kyeong-Min HamDepartment of Bioscience and Biotechnology, Konkuk University, Seoul, 05029, South Korea.
Sung Gun LeeDepartment of Chemistry Education, Seoul National University, Seoul, 08826, South Korea.
Sang Hun LeeDepartment of Chemical and Biological Engineering, Hanbat National University, Deajeon, 34158, South Korea.
Homan KangDepartment of Radiology, Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.
Hak Soo ChoiDepartment of Radiology, Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.
Dae Hong JeongDepartment of Chemistry Education, Seoul National University, Seoul, 08826, South Korea.
Hyejin ChangDivision of Science Education, Kangwon National University, Chuncheon, 24341, South Korea. hjchang@kangwon.ac.kr.
Dong-Eun KimDepartment of Bioscience and Biotechnology, Konkuk University, Seoul, 05029, South Korea. kimde@konkuk.ac.kr.
Bong-Hyun JunDepartment of Bioscience and Biotechnology, Konkuk University, Seoul, 05029, South Korea. bjun@konukuk.ac.kr.ORCID http://orcid.org/0000-0001-6556-7946

Funding

National Research Foundation of Korea NRF-2017H1A2A1044051
6 · The paper itself

Abstract

backgroundTo take advantages, such as multiplex capacity, non-photobleaching property, and high sensitivity, of surface-enhanced Raman scattering (SERS)-based in vivo imaging, development of highly enhanced SERS nanoprobes in near-infrared (NIR) region is needed. A well-controlled morphology and biocompatibility are essential features of NIR SERS nanoprobes. Gold (Au)-assembled nanostructures with controllable nanogaps with highly enhanced SERS signals within multiple hotspots could be a breakthrough.

resultsAu-assembled silica (SiO

conclusionsSiO

Indexed as

Metal NanoparticlesNanoparticlesAnimalsGoldMiceMice, NudeSilicon DioxideSpectrum Analysis, RamanGoldSilicon DioxideGold nanoparticleHotspotIn vivo imagingNanogapSurface-enhanced Raman spectroscopy (SERS)

Identifiers

PMID35279134
PMCPMC8917682

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.