Evidence map›Paper›PMID 35279936›Full record

ReviewMolecular nutrition & food research2022

Cardioprotective Properties of Phenolic Compounds: A Role for Biological Rhythms.

Cristina Torres-Fuentes, Manuel Suárez, Gerard Aragonès, Miquel Mulero, Javier Ávila-Román, Anna Arola-Arnal, Maria Josepa Salvadó, Lluís Arola, Francisca Isabel Bravo, Begoña Muguerza

Abstract readReview
In one paragraph

Review in Molecular nutrition & food research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Biomedicines · 2025
    Article
  8. Article
  9. Circadian rhythms in cardiovascular disease.European heart journal · 2025
    Review
  10. Review
  11. Review
  12. Natural Compounds for Preventing Age-Related Diseases and Cancers.International journal of molecular sciences · 2024
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cristina Torres-FuentesNutrigenomics Research Group, Departament de Bioquímica i Biotecnologia, Universitat Rovira i Virgili, Tarragona, 43007, Spain.ORCID 0000-0002-2917-6910
Manuel SuárezNutrigenomics Research Group, Departament de Bioquímica i Biotecnologia, Universitat Rovira i Virgili, Tarragona, 43007, Spain.ORCID 0000-0003-0122-8253
Gerard AragonèsNutrigenomics Research Group, Departament de Bioquímica i Biotecnologia, Universitat Rovira i Virgili, Tarragona, 43007, Spain.ORCID 0000-0001-8657-5726
Miquel MuleroNutrigenomics Research Group, Departament de Bioquímica i Biotecnologia, Universitat Rovira i Virgili, Tarragona, 43007, Spain.ORCID 0000-0003-2545-2065
Javier Ávila-RománNutrigenomics Research Group, Departament de Bioquímica i Biotecnologia, Universitat Rovira i Virgili, Tarragona, 43007, Spain.
Anna Arola-ArnalNutrigenomics Research Group, Departament de Bioquímica i Biotecnologia, Universitat Rovira i Virgili, Tarragona, 43007, Spain.ORCID 0000-0001-6529-1345
Maria Josepa SalvadóNutrigenomics Research Group, Departament de Bioquímica i Biotecnologia, Universitat Rovira i Virgili, Tarragona, 43007, Spain.ORCID 0000-0003-3883-3326
Lluís ArolaNutrigenomics Research Group, Departament de Bioquímica i Biotecnologia, Universitat Rovira i Virgili, Tarragona, 43007, Spain.ORCID 0000-0003-2767-1974
Francisca Isabel BravoNutrigenomics Research Group, Departament de Bioquímica i Biotecnologia, Universitat Rovira i Virgili, Tarragona, 43007, Spain.ORCID 0000-0002-6468-3088
Begoña MuguerzaNutrigenomics Research Group, Departament de Bioquímica i Biotecnologia, Universitat Rovira i Virgili, Tarragona, 43007, Spain.ORCID 0000-0001-7384-8588

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases (CVD) are the leading cause of deaths worldwide and their prevalence is continuously increasing. Available treatments may present several side effects and therefore the development of new safer therapeutics is of interest. Phenolic compounds have shown several cardioprotective properties helpful in reducing different CVD risk factors such as inflammation, elevated blood pressure, hyperlipidemia, or endothelial dysfunction. These factors are significantly influenced by biological rhythms which are in fact emerging as key modulators of important metabolic and physiological processes. Thus, increased events of CVD have been observed under circadian rhythm disruption or in winter versus other seasons. These rhythms can also affect the functionality of phenolic compounds. Indeed, different effects have been observed depending on the administration time or under different photoperiods. Therefore, in this review the focus will be on the potential of phenolic compounds as therapeutics to prevent CVD via biological rhythm modulation.

Indexed as

Cardiovascular DiseasesCircadian RhythmHumansInflammationPhenolsPhenolscardiovascular diseasescircadian rhythmsendothelial functionoxidative stresspolyphenols

Identifiers

PMID35279936
PMCPMC9786928

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.