Evidence mapPaperPMID 35284164Full record

ArticleBiomedical optics express2022

Depth-resolved vascular profile features for artery-vein classification in OCT and OCT angiography of human retina.

Tobiloba Adejumo, Tae-Hoon Kim, David Le, Taeyoon Son, Guangying Ma, Xincheng Yao

Abstract read
In one paragraph

Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tobiloba AdejumoDepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID https://orcid.org/0000-0001-8500-2168
Tae-Hoon KimDepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID https://orcid.org/0000-0002-4391-4860
David LeDepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Taeyoon SonDepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Guangying MaDepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID https://orcid.org/0000-0002-7990-1420
Xincheng YaoDepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID https://orcid.org/0000-0002-0356-3242

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · UNIVERSITY OF ILLINOIS AT CHICAGO · 1985 to 2025
$3.9M
Differential artery-vein analysis in OCT angiography for objective classification of diabetic retinopathyR01EY030842 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Jennifer Irene Lim, XINCHENG YAO · 2023 to 2023
$363k
Functional tomography of neurovascular coupling interactions in healthy and diseased retinasR01EY030101 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI XINCHENG YAO · 2022 to 2022
$304k
NEI NIH HHS P30 EY001792NEI NIH HHS R01 EY023522NEI NIH HHS R01 EY030101NEI NIH HHS R01 EY030842
6 · The paper itself

Abstract

This study is to characterize reflectance profiles of retinal blood vessels in optical coherence tomography (OCT), and to test the potential of using these vascular features to guide artery-vein classification in OCT angiography (OCTA) of the human retina. Depth-resolved OCT reveals unique features of retinal arteries and veins. Retinal arteries show hyper-reflective boundaries at both upper (inner side towards the vitreous) and lower (outer side towards the choroid) walls. In contrast, retinal veins reveal hyper-reflectivity at the upper boundary only. Uniform lumen intensity was observed in both small and large arteries. However, the venous lumen intensity was dependent on the vessel size. Small veins exhibit a hyper-reflective zone at the bottom half of the lumen, while large veins show a hypo-reflective zone at the bottom half of the lumen.

Identifiers

PMID35284164
PMCPMC8884205

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.