ArticleFrontiers in nutrition2022
Impact of Overhydration on Left Ventricular Hypertrophy in Patients With Chronic Kidney Disease.
Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.
- On Whether Ca-125 Is the Answer for Diagnosing Overhydration, Particularly in End-Stage Kidney Disease Patients-A Systematic Review.International journal of molecular sciences · 2024Pooled it
- Bioimpedance Indices of Fluid Overload and Cardiorenal Outcomes in Heart Failure and Chronic Kidney Disease: a Systematic Review.Journal of cardiac failure · 2022Pooled it
- Flow-driven left ventricular remodelling in long-term haemodialysis: a multicenter model of arteriovenous access-induced cardiac load.Renal failure · 2026Article
- The association between extracellular fluid volume and sympathetic nervous system activity in patients with chronic kidney disease.American journal of physiology. Renal physiology · 2026Article
- Association between Neutrophil-to-Lymphocyte ratio and left ventricular hypertrophy in chronic kidney disease patients: a cross-sectional study.BMC cardiovascular disorders · 2025Article
- The value of bioimpedance analysis in the assessment of hydration and nutritional status in children on chronic peritoneal dialysis.Renal failure · 2024Article
- High sodium intake and fluid overhydration predict cardiac structural and functional impairments in chronic kidney disease.Frontiers in nutrition · 2024Article
- The mediating role of the left ventricular mass index on the relationship between the fluid balance and left ventricular diastolic function in patients with chronic kidney disease.Kidney research and clinical practice · 2024Article
- Loop diuretics improve conditions of dialysis inception in advanced CKD: an observational cohort study.Journal of nephrology · 2023Observational
Corrections and comments
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Volume overload is a frequent feature related to left ventricular hypertrophy (LVH) in dialysis patients, but its influence on patients with chronic kidney disease (CKD) not on dialysis has not been accurately uncovered. This article was to examine the relationship between overhydration (OH) and LVH in patients with CKD not yet on dialysis. Methods: A total of 302 patients with CKD stages 1-4 were included. Participants were divided into different subgroups according to occurring LVH or not, and OH tertiles. Clinical and laboratory parameters were compared among groups. Spearman correlation analyses were adopted to explore the relationships of echocardiographic findings with the clinical and laboratory characteristics. Binary logistic regression models were performed to estimate the odds ratios (ORs) for the associations between OH and LVH. Restricted cubic splines were implemented to assess the possible non-linear relationship between OH and LVH. LVH was defined as left ventricular mass index (LVMI) >115 g/m Results: Of the enrolled patients with CKD, the mean age was 45.03 ± 15.14 years old, 165 (54.6%) cases were men, and 65 (21.5%) cases had LVH. Spearman correlation analyses revealed that OH was positively correlated with LVMI ( Conclusion: These findings suggest that a higher level of OH was associated with a higher occurrence of LVH in patients with CKD not on dialysis, especially in patients with CKD stages 1-2.
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